MicroRNA-542-3p targets Pten to inhibit the myoblasts proliferation but suppresses myogenic differentiation independent of targeted Pten
Dandan Li,
Yongqi Yue,
Xinxin Feng
et al.
Abstract:Background
Non-coding RNA is a key epigenetic regulation factor during skeletal muscle development and postnatal growth, and miR-542-3p was reported to be conserved and highly expressed in the skeletal muscle among different species. However, its exact functions in the proliferation of muscle stem cells and myogenesis remain to be determined.
Methods
Transfection of proliferative and differentiated C2C12 cells used miR-542-3p mimic and inhibitor. R… Show more
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