MicroRNA-155 targets SOCS1 to inhibit osteoclast differentiation during orthodontic tooth movement
Yao Jiao,
Sicong Mi,
Xiaoyan Li
et al.
Abstract:Background
MicroRNA-155 (miR-155) is a multifunctional miRNA whose expression is known to be involved in a range of physiological and pathological processes. Its association with several oral diseases has been established. However, the specific role of miR-155 in orthodontic tooth movement remains unclear. In this study, we investigated the impact of miR-155 on osteoclast differentiation and orthodontic tooth movement models, aiming to explore the underlying mechanisms.
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