Abstract:Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease
with the decreasing proportion of regulatory T (Treg) cells. Previous
studies have shown that microRNAs (miRNAs, miR) act as key regulators of
Treg cells. In this study, we assessed the involvement of miR-143-3p on
Treg cells differentiation and function in the RA progress. We reported
that the expression of miR-143-3p has been negatively associated with RA
disease activity, and actively correlated with anti-inflammatory
cytokine IL-10, whi… Show more
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