Micropulse laser trabeculoplasty on pseuodexfoliation glaucoma patients under topical prostaglandin analogue monotherapy: 1-year results

Makri, Olga Ε; Pallikari, Athina; Pagoulatos, Dionysios; Kagkelaris, Konstantinos; Kostopoulou, Elli V.; Georgakopoulos, Constantinos D.

doi:10.1007/s00417-018-4195-2

Cited by 9 publications

(10 citation statements)

References 18 publications

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“…Patients with open-angle glaucoma that was not managed by topical drugs alone were the focus of MDLT trials. The majority of the studies included all kinds of open-angle glaucoma, with only a few of them specifically targeting primary open-angle glaucoma, [ 23 , 29 , 54 ] and only one study regarding exclusively secondary open-angle glaucoma [ 30 ].…”

Section: Mdlt For Primary Open-angle Glaucomamentioning

confidence: 99%

“…However, concerns regarding IOP inter-operator variability have arisen because of the lack of observable treatment endpoints with MDLT, such as the bubbles seen in the SLT technique. Because earlier investigations have shown contradictory findings and irradiation circumstances are not uniform, the efficiency of MDLT requires additional confirmation [ 27 , 28 , 29 , 30 ].…”

Section: Introductionmentioning

confidence: 99%

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Spotlight on MicroPulse Laser Trabeculoplasty in Open-Angle Glaucoma: What’s on? A Review of the Literature

Gambini

Carlà

Caporossi

et al. 2022

Vision

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Glaucoma is the most common cause of permanent blindness in the world, caused by a progressive optic neuropathy. Patients with glaucoma are often treated with topical medicines therapy in order to reduce intra-ocular pressure (IOP). On the other hand, laser therapies, with the introduction of Argon Laser Trabeculoplasty (ALT) and successively with Selective Laser Trabeculoplasty (SLT), were reported to be effective in IOP control, with low adverse effect rates. In recent years, the micropulse laser, a subthreshold laser technology, was introduced with the goal of reducing side effects while maintaining the effectiveness of the laser treatments. Several studies focused on Micropulse Diode Laser Trabeculoplasty (MDLT) in open-angle glaucoma, to evaluate its effectiveness and possible side effects. Promising results were reported, but irradiation circumstances have not been standardized yet and its role as a substitute for previous laser techniques has yet to be defined. As a result, the goal of this review was to analyze the physical principles at the basis of MDLT and to frame it in the open-angle glaucoma management setting, highlighting the advantages and shortfalls of this technique.

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Section: Mdlt For Primary Open-angle Glaucomamentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Spotlight on MicroPulse Laser Trabeculoplasty in Open-Angle Glaucoma: What’s on? A Review of the Literature

Gambini

Carlà

Caporossi

et al. 2022

Vision

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“…Several clinical trials have been carried out to evaluate the e cacy and safety of MLT. However, the standard protocol for MLT was still not available, and studies continued to explore it (4)(5)(6)(7)(8). Besides, even though some papers evaluated MLT' e cacy, there's still no data showed how long the IOP-reduction effect could last (9).…”

Section: Introductionmentioning

confidence: 99%

Micropulse Laser Trabeculoplasty On Glaucoma Patients: Average 35 Months Follow-Up Results

Yang¹,

Huang²,

Liao³

et al. 2021

Preprint

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Background: Glaucoma is a group of eye diseases that can damage the optic nerve and cause vision loss. A novel technology micropulse laser trabecular plasty (MLT) can use duty-circle subvisible laser pulses to treat glaucoma. The aim of this study is to evaluate the efficacy of 360° MLT to alleviate intraocular pressure (IOP) in patients with glaucoma.Methods: This was a single-center prospective study on patients treated with 360° MLT using a Diode True-Yellow 577-nm Laser with MicroPulse technology. All the patients were recruited from the Department of Ophthalmology. Follow-up visits were carried out at 1 day, 1 week, 1 month, 3 months, 6 months, 18 months, and 36 months after the procedure. Best-corrected visual acuity (BCVA), Intraocular pressure (IOP), and vertical cup-to-disc ratio (C/D ratio) were measured during the follow-up. Repeated-measures analysis of variance (ANOVA) and Kaplan–Meier analysis were performed to evaluate the outcomes.Results: A total of 39 eyes from 26 patients were included in this study (10 men/15 women). The average age of patients was 41.47±14.39 years old, and the baseline IOP was 21.13 ± 7.75 mmHg. MLT significantly reduced the IOP at 1 day (range 15.61–19.01, P=0.0218), 3 months (range 16.47–19.22, P=0.0390), and 6 months (range 15.38–18.56, P=0.0332) compared with the baseline. However, by the end of the study, only 21.88% of patients demonstrated a ≥ 20% IOP reduction, while seven eyes needed further laser or surgical treatment. Conclusions: Micropulse laser trabeculoplasty could reduce IOP in patients with glaucoma or ocular hypertension for a short period, but its lowering efficiency was limited up to 6 months of the follow-up period.

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“…Electromagnetic energy generated by argon laser gets converted into thermal energy. This causes thermal burn of the trabecular meshwork, which consecutively improves aqueous humor resorption ( 6 , 7 ). In some cases, argon laser trabeculotomy can be used primarily.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Primary Argon Laser Trabeculoplasty on Intraocular Pressure Reduction and Quality of Life in Patients with Pseudoexfoliation Glaucoma

Todorović

Vulović

Srećković³

et al. 2021

ACC

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Micropulse laser trabeculoplasty on pseuodexfoliation glaucoma patients under topical prostaglandin analogue monotherapy: 1-year results

Cited by 9 publications

References 18 publications

Spotlight on MicroPulse Laser Trabeculoplasty in Open-Angle Glaucoma: What’s on? A Review of the Literature

Spotlight on MicroPulse Laser Trabeculoplasty in Open-Angle Glaucoma: What’s on? A Review of the Literature

Micropulse Laser Trabeculoplasty On Glaucoma Patients: Average 35 Months Follow-Up Results

The Effect of Primary Argon Laser Trabeculoplasty on Intraocular Pressure Reduction and Quality of Life in Patients with Pseudoexfoliation Glaucoma

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