Microproteins/micropeptides dysregulation contributes to cancer progression and development: A mechanistic review
Paul Rodrigues,
Harun Bangali,
Eyhab Ali
et al.
Abstract:Microproteins, known as micropeptides, are small protein molecules encoded by short open reading frames. These recently identified molecules have been proven to be an essential part of the human proteome that participates in multiple processes, such as DNA repair, mitochondrial respiration, and regulating different signaling pathways. A growing body of studies has evidenced that microproteins exhibit dysregulated expression levels in various malignancies and contribute to tumor progression. It has been reporte… Show more
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