Abstract:Systemic fungal infections are responsible for high morbidity and mortality especially in immune-sensitive patients. The treatment with the available antifungal substances is long and causes various collateral effects, which justifies the search for new antifungal agents. In Brazil, endemic diseases, such as Tuberculosis, Leishmaniasis and Chagas Disease, also need new drugs to increase the possibilities of their cure. The biodiversity of microorganisms found in the ecosystems provide excellent perspectives fo… Show more
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