1994
DOI: 10.1002/ajim.4700250124
|View full text |Cite
|
Sign up to set email alerts
|

Microorganism‐induced or enhanced mediator release: A possible mechanism in organic dust related diseases

Abstract: Bacteria were found to trigger mediator release, including histamine, leukotriene B4, and prostaglandin D2. Furthermore, histamine release caused by allergens as well as by nonimmunological reactions was enhanced by bacteria, endotoxins, and spores from molds. Mediator release and its enhancement play a crucial role for bronchoconstriction and inflammatory events in the airways. These effects of allergens, microorganisms, and other noxious agents in dusts may, therefore, in concert be responsible for the sympt… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

1997
1997
2006
2006

Publication Types

Select...
5

Relationship

0
5

Authors

Journals

citations
Cited by 7 publications
(1 citation statement)
references
References 12 publications
0
1
0
Order By: Relevance
“…[41][42][43][44] In addition, LPS acts synergistically with allergen resulting in a magnification of specific allergen-induced mediator release. [45][46][47] Thus, problems of LPS contamination on natural latex products are not only pyrogenicity, but may also be associated with other adverse reactions, such as tissue irritation and induction or enhancement of latex allergy. 48,49 …”
Section: Discussionmentioning
confidence: 99%
“…[41][42][43][44] In addition, LPS acts synergistically with allergen resulting in a magnification of specific allergen-induced mediator release. [45][46][47] Thus, problems of LPS contamination on natural latex products are not only pyrogenicity, but may also be associated with other adverse reactions, such as tissue irritation and induction or enhancement of latex allergy. 48,49 …”
Section: Discussionmentioning
confidence: 99%