Micronutrients and their effects on Horticultural crop quality, productivity and sustainability

Ahmed, Nazir; Zhang, Baige; Chachar, Zaid; Li, Juan; Xiao, Gengsheng; Wang, Qin; Hayat, Faisal; Deng, Lansheng; Narejo, Mehar-un-Nisa; Bozdar, Bilqees; Tu, Panfeng

doi:10.1016/j.scienta.2023.112512

Cited by 31 publications

(14 citation statements)

References 179 publications

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“…The interconnected pathways of iron metabolism, anemia, and HIV create a dynamic landscape where disruptions in one element reverberate across the others. [ 54 ] Unraveling the complexities of this interplay is crucial for devising effective therapeutic strategies that not only address anemia but also contribute to the comprehensive care of individuals living with HIV. As research advances, a deeper understanding of these relationships will pave the way for more precise and nuanced interventions.…”

Section: Iron Metabolism In Anemia and Hivmentioning

confidence: 99%

Anemia, iron, and HIV: decoding the interconnected pathways: A review

Obeagu,

Ukibe

et al. 2024

Medicine

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This review delves into the intricate relationship between anemia, iron metabolism, and human immunodeficiency virus (HIV), aiming to unravel the interconnected pathways that contribute to the complex interplay between these 3 entities. A systematic exploration of relevant literature was conducted, encompassing studies examining the association between anemia, iron status, and HIV infection. Both clinical and preclinical investigations were analyzed to elucidate the underlying mechanisms linking these components. Chronic inflammation, a hallmark of HIV infection, disrupts iron homeostasis, impacting erythropoiesis and contributing to anemia. Direct viral effects on bone marrow function further compound red blood cell deficiencies. Antiretroviral therapy, while essential for managing HIV, introduces potential complications, including medication-induced anemia. Dysregulation of iron levels in different tissues adds complexity to the intricate network of interactions. Effective management of anemia in HIV necessitates a multifaceted approach. Optimization of antiretroviral therapy, treatment of opportunistic infections, and targeted nutritional interventions, including iron supplementation, are integral components. However, challenges persist in understanding the specific molecular mechanisms governing these interconnected pathways. Decoding the interconnected pathways of anemia, iron metabolism, and HIV is imperative for enhancing the holistic care of individuals with HIV/AIDS. A nuanced understanding of these relationships will inform the development of more precise interventions, optimizing the management of anemia in this population. Future research endeavors should focus on elucidating the intricate molecular mechanisms, paving the way for innovative therapeutic strategies in the context of HIV-associated anemia.

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Section: Iron Metabolism In Anemia and Hivmentioning

confidence: 99%

Anemia, iron, and HIV: decoding the interconnected pathways: A review

Obeagu,

Ukibe

et al. 2024

Medicine

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“…These alterations have a cytotoxic, genotoxic, or mutagenic effect on living systems, including plants, animals, and human beings. , Metals that are essential for life are categorized as essential microelements for plant growth, such as zinc (Zn), iron (Fe), copper (Cu), manganese (Mn), magnesium (Mg), nickel (Ni), and molybdenum (Mo) . On the other hand, there are some nonessential elements such as chromium (Cr), lead (Pb), cadmium (Cd), cobalt (Co), mercury (Hg), selenium (Se), and silver (Ag) whose biological functions are not yet clear . Minimum quantities of essential metals in plants are necessary for normal functioning; however, an increased concentration of these metals (both essential and nonessential) can cause toxicity and hamper plant growth. , …”

Section: Introductionmentioning

confidence: 99%

“…3 On the other hand, there are some nonessential elements such as chromium (Cr), lead (Pb), cadmium (Cd), cobalt (Co), mercury (Hg), selenium (Se), and silver (Ag) whose biological functions are not yet clear. 3 Minimum quantities of essential metals in plants are necessary for normal functioning; however, an increased concentration of these metals (both essential and nonessential) can cause toxicity and hamper plant growth. 4,5 In nature, plants respond to different stresses by changing their morphological, physiological, or biochemical reactions.…”

Section: Introductionmentioning

confidence: 99%

“…In recent decades, anthropogenic activities have altered the natural biogeochemical cycles, which led to the accumulation of heavy metals�non-biodegradable, persistent chemical compounds having an atomic mass of 20 and a density greater than 5 g/cm 3 . These alterations have a cytotoxic, genotoxic, or mutagenic effect on living systems, including plants, animals, and human beings.…”

Section: Introductionmentioning

confidence: 99%

“…In recent decades, anthropogenic activities have altered the natural biogeochemical cycles, which led to the accumulation of heavy metalsnon-biodegradable, persistent chemical compounds having an atomic mass of 20 and a density greater than 5 g/cm 3 . These alterations have a cytotoxic, genotoxic, or mutagenic effect on living systems, including plants, animals, and human beings. , Metals that are essential for life are categorized as essential microelements for plant growth, such as zinc (Zn), iron (Fe), copper (Cu), manganese (Mn), magnesium (Mg), nickel (Ni), and molybdenum (Mo) . On the other hand, there are some nonessential elements such as chromium (Cr), lead (Pb), cadmium (Cd), cobalt (Co), mercury (Hg), selenium (Se), and silver (Ag) whose biological functions are not yet clear .…”

Section: Introductionmentioning

confidence: 99%

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Plant Defense Strategies and Biomarkers against Heavy Metal-Induced Stress: A Comprehensive Review

Tyagi,

Dhiman,

Dhiman

et al. 2024

ACS Agric. Sci. Technol.

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Plants respond to environmental pollutants and experience several abiotic stresses, among which heavy metal stress has been a serious concern in the global scientific community due to its yield-limiting effects on crop plants. Heavy metals intrude into the plant defense system and interfere with the cellular machinery, leading to metal toxicity and resulting in plant growth inhibition or death. Plants employ several counterbalance strategies, such as the formation of phytochelatins or metallothionein metal complexes, or vacuolar sequestration of ligand–metal complexes, etc., to combat heavy metal stress. Additionally, microbes present in the rhizospheric region share a special relationship with plants and immobilize heavy metals to improve plant health. Thus, the precise detection of heavy metals in adjoining environments is crucial to develop strategic defense strategies for sustainable agriculture. In this context, plant-based biomarkers have evolved as a promising approach. This review sheds light on heavy metal stress, various defense strategies employed by plants, and potential biomarkers used to detect heavy metal stresses and tries to draw a possible roadmap toward smart and sustainable agriculture.

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