Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study

Saadawi, Amr N; Esawy, Abdulla M; Kandeel, Abdalla H; El-Sayed, Walaa

doi:10.1111/jocd.12827

Cited by 27 publications

(20 citation statements)

References 15 publications

(19 reference statements)

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“…Results showed overall statistically significant improvement in acne scarring in all three groups (P<0.05). This study also showed statistically significant increase in frequency of very good satisfactory and objective rate in Group III compared to Groups I and II, and in Group I compared to Group II (P<0.05) [6].…”

Section: Acne Scarsupporting

confidence: 64%

Untitled

2018

IJCED

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Introduction: Microneedling, needling and acupuncture are some of the upcoming treatment modalities used in the management conditions. It has been postulated that in microneedling and needling, superficial trauma to the epidermis leads to the production of inflammatory cascade, resulting in production of growth factors that lead to skin rejuvenation.Objective: Our aim of this review paper is to review the current evidence available for the efficacy of microneedling, needling and acupuncture in the management of skin conditions. Method:We reviewed 21 papers which were a combination of pilot studies, systematic reviews, randomised controlled trials and prospective studies. Protocol studies for systematic reviews and non-English publications were excluded in this review. Discussion:We found that microneedling and needling as adjunct therapies are more effective than monotherapy for the management of skin conditions. Meanwhile, the evidence on the efficacy of acupuncture in management of skin conditions is debatable. However, we noted that in all the papers we reviewed, sample sizes are small and risk of bias is high due to poor disclosure of methodology and poor blinding due to the practical nature of the interventions assessed. Conclusion:We conclude that although evidence has shown significant improvement in using microneedling and needling as adjunct therapies, large randomised controlled trials need to be held. This is similar to the evidence for acupuncture as well.

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Section: Acne Scarsupporting

confidence: 64%

Untitled

2018

IJCED

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“…Studies that only used the PROM as an outcome measurement instrument were excluded, but study details were tabulated, per protocol. We identified 188 studies that reported treatment satisfaction as an outcome: 91 on treatment of acne 68–158 and 97 on treating acne scars (a possible sequela of acne) 159–255 . These numbers show that clinicians and researchers do consider treatment satisfaction as an important outcome.…”

Section: Resultsmentioning

confidence: 99%

Identifying and appraising patient‐reported outcome measures on treatment satisfaction in acne: a systematic review*

Zuuren

Arents²,

Miklas

et al. 2020

Br J Dermatol

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Background After dermatitis, acne is the next skin disease to contribute most to the burden of skin diseases worldwide. Recently, seven core outcome domains have been identified, which together form an Acne Core Outcome Set (ACORN). One of these was satisfaction with acne treatment. Objectives To identify studies that described the development of patient-reported outcome measures (PROMS), evaluated one or more measurement properties of a PROM, or evaluated the interpretability of a PROM in patients with acne regarding treatment satisfaction. Methods The COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN) search strategy for identifying PROMS on acne treatment satisfaction was used. We searched PubMed, MEDLINE, Embase, LILACS, Web of Science, Cochrane Library, Emcare, PsycINFO and Academic Search premier (June 2020). Study selection, data extraction and assessment of methodological quality according to COSMIN guidance were carried out independently by two authors. Results Only one study could be included, describing the development of a treatment satisfaction measure in patients with acne. The development was assessed as inadequate and data on measurement properties were lacking. Additionally, we found 188 studies reporting treatment satisfaction solely as an outcome, using a wide variety of methods, none of them standardized or validated. Conclusions We could not find a PROM on treatment satisfaction to recommend for a core outcome set in acne. There is an unmet need for a PROM on treatment satisfaction in acne that is robustly developed, designed and validated.What is already known about this topic?• Core outcome sets are consensus-based minimum outcome measures that should be reported in clinical trials of a specific disease or target condition.

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“…A comparative study conducted between microneedling by Dermapen versus GA peel versus the combination of both suggests combination to be more effective. [ 34 ]…”

Section: Icroneedlingmentioning

confidence: 99%