Microneedling

Khetarpal, Shilpi; Soh, Jonathan; Velez, Mara Weinstein; Haimovic, Adele

doi:10.1016/j.yacs.2019.02.003

Cited by 2 publications

(7 citation statements)

References 37 publications

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“…Micro channels thus form as a result of the physical shock that triggers dermal regeneration by inducing fibroblast growth factor, platelet-derived growth factor, and transforming growth factor (TGF)-a and TGF-b 3 . This triggers fibroblast proliferation and migration and consequently leads to neovascularization and neocollagenesis.…”

Section: Mechanism Of Microneedlingmentioning

confidence: 99%

“…Hydrogel microneedles are generally easier and more cost-effective to make from materials that are more biocompatible and have FDA approval 31 . Usage in health care facilities 3 .…”

Section: Hydrogel Microneedlesmentioning

confidence: 99%

“…Pen-shaped and enable for easy adjustment of needle penetration depths Disposable, reducing the danger of infection and allowing for the treatment of small regions 3 .…”

Section: Automated Devicesmentioning

confidence: 99%

“…To treat scars, wrinkles, and skin laxity Fractional radio-frequency type, uses insulated needles that release radiofrequency currents upon skin penetration, resulting in dermal remodelling and neo-collagenesis 3 .…”

Section: Microneedles With Radio-frequency and Light-emitting Diodesmentioning

confidence: 99%

“…Neovascularization and neocollagenesis promote skin rejuvenation. Patients who are concerned about aesthetic changes caused by injury, sickness, or aging have recently been treated using this technique 3 . Solid, dissolving, hydrogel-coated, and hollow microneedles are some of the varieties of microneedles 4 .…”

Section: Introductionmentioning

confidence: 99%

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Microneedles-A new paradigm in transdermal delivery of therapeutic agents

Bhattacharyya¹,

Kotresh²

2022

Pharm Sci Asia

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Microneedles are a new mode of transdermal delivery system that delivers the drug through micron-size pathways caused by disruption of the epidermis. It is an effective procedure with an array of applications in dermatology and drug delivery with a low side effect profile. Microneedles deliver the drug in the epidermis or upper part of the dermis, bypassing the toughest barrier of the stratum corneum, and resulting in a painless delivery. Microneedles are being investigated for the delivery of hormones, vaccines, peptides, and cosmetics. They are fabricated as dissolvable, solid, coated, or hollow depending on the type of drug loading. This review is a comprehensive collection of various aspects of microneedles. The authors focus to enlighten the readers on the mechanism of dermal penetration of microneedles, their fabrication materials, types, design strategy, specificity, and manufacturing. There are a few products already captured the market. A lot of research and clinical studies are yet to establish the scale-up and clinical efficacy of the product. They can be served as a novel modality for the enhancement of topical delivery of drugs at a low cost, well tolerated, and with low profiles of side effects.

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Section: Mechanism Of Microneedlingmentioning

confidence: 99%

“…Hydrogel microneedles are generally easier and more cost-effective to make from materials that are more biocompatible and have FDA approval 31 . Usage in health care facilities 3 .…”

Section: Hydrogel Microneedlesmentioning

confidence: 99%

“…Pen-shaped and enable for easy adjustment of needle penetration depths Disposable, reducing the danger of infection and allowing for the treatment of small regions 3 .…”

Section: Automated Devicesmentioning

confidence: 99%

Section: Microneedles With Radio-frequency and Light-emitting Diodesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Microneedles-A new paradigm in transdermal delivery of therapeutic agents

Bhattacharyya¹,

Kotresh²

2022

Pharm Sci Asia

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Therapeutics of microneedling for skin repair

Sreeharsha

gharsan

2022

AJPS

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The microneedling technique was initially introduced for skin rejuvenation in cosmetology. The technique is minimally invasive and therefore explored for the treatment of multiple dermatological conditions. High effectiveness, very less side effects and quick recovery time are the benefits of skin microneedling as a cosmetic, and medical treatment. Over the last two decades, the applications of microneedling in skin science have grown drastically. The technique is effective in the treatment of acne scar, vitiligo, alopecia, melasma, and skin cancer. The current review focuses on the cosmetic as well as therapeutic applications of microneedling for the treatment of various skin problems.

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Microneedling

Cited by 2 publications

References 37 publications

Microneedles-A new paradigm in transdermal delivery of therapeutic agents

Microneedles-A new paradigm in transdermal delivery of therapeutic agents

Therapeutics of microneedling for skin repair

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