Microneedles with integrated magnetoresistive sensors: A precision tool in biomedical instrumentation

Valadeiro, João; Silva, Marília; Freitas, P. P.; Martins, Marco; Gaspar, J.; Sebastião, Ana M.

doi:10.1109/sas.2017.7894041

Cited by 8 publications

(13 citation statements)

References 14 publications

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“…Magnetoresistive sensors have a great significance in industry. They are utilized in a vast spectrum of applications such as compass-, biomedical-, automotive-and aerospace applications [1][2][3][4]. The most prominent sensor design is the spin valve principle with a basic common structure of two adjacent magnetic layers separated by a spacer layer.…”

Section: Introductionmentioning

confidence: 99%

Comparison of Sensitivity and Low-Frequency Noise Contributions in Giant-Magnetoresistive and Tunneling-Magnetoresistive Spin-Valve Sensors with a Vortex-State Free Layer

et al. 2018

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Magnetoresistive spin valve sensors based on the giant-(GMR) and tunnelling-(TMR) magnetoresisitve effect with a flux-closed vortex state free layer design are compared by means of sensitivity and low frequency noise. The vortex state free layer enables high saturation fields with negligible hysteresis, making it attractive for applications with a high dynamic range. The measured GMR devices comprise lower pink noise and better linearity in resistance but are less sensitive to external magnetic fields than TMR sensors. The results show a comparable detectivity at low frequencies and a better performance of the TMR minimum detectable field at frequencies in the white noise limit.

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Section: Introductionmentioning

confidence: 99%

Comparison of Sensitivity and Low-Frequency Noise Contributions in Giant-Magnetoresistive and Tunneling-Magnetoresistive Spin-Valve Sensors with a Vortex-State Free Layer

et al. 2018

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“…GMR based technology is the preferred choice for low magnetic fields detection with high spatial resolution. The maturity of GMR sensor fabrication relies on large-scale methods, and offers many advantages: Smart system integration with multiple components of Si-based integrated circuits in small platforms with decreased operation difficulty and power consumption, such as lab-on-a-chip devices [ 39 , 40 ], signal post-process modules and communication modules; Miniaturized structures without sensitivity loss providing increased spatial resolution in weak biomagnetic fields sensing; Room-temperature operation without bulky cooling systems and the associated expensive costs; Array applications with robust spatial measurements and compact systems [ 2 , 41 ]; Real-time and multi-mode process based on high compatibility with standard CMOS processes, such as simultaneous electronic and magnetic readout [ 28 , 42 ]. …”

Section: Integrated Gmr Sensors Towards Bmsimentioning

confidence: 99%

“…Real-time and multi-mode process based on high compatibility with standard CMOS processes, such as simultaneous electronic and magnetic readout [ 28 , 42 ].…”

Section: Integrated Gmr Sensors Towards Bmsimentioning

confidence: 99%

“…This will provide micron-size spatial resolution in neurophysiology studies. As summarized in Table 1 , two research groups have reported successful validations of local recording of biomagnetic signals using integrated GMR-based silicon probes [ 21 , 22 , 23 , 28 , 85 , 86 ].…”

Section: Integrated Gmr Systems For In Vivo/vitro Biomagnetic Signmentioning

confidence: 99%

“…High quality integrated GMR systems combined with multiple technologies have been proposed [ 21 , 22 , 23 ]. In recent years, an extensive research activity has been triggered to exploit the potentials of integrated GMR in ultra-low biomagnetic signal detection [ 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 ]. Without involving increased cost and complicated structure, integrated GMR brings aggregative performance improvements [ 23 , 28 , 29 ] in the fabrication process, structure size, anti-noise ability and sensitivity, taking advantages of multiple technologies and the inherent properties of GMR.…”

Section: Introductionmentioning

confidence: 99%

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Integrated Giant Magnetoresistance Technology for Approachable Weak Biomagnetic Signal Detections

Shen

2018

Sensors

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With the extensive applications of biomagnetic signals derived from active biological tissue in both clinical diagnoses and human-computer-interaction, there is an increasing need for approachable weak biomagnetic sensing technology. The inherent merits of giant magnetoresistance (GMR) and its high integration with multiple technologies makes it possible to detect weak biomagnetic signals with micron-sized, non-cooled and low-cost sensors, considering that the magnetic field intensity attenuates rapidly with distance. This paper focuses on the state-of-art in integrated GMR technology for approachable biomagnetic sensing from the perspective of discipline fusion between them. The progress in integrated GMR to overcome the challenges in weak biomagnetic signal detection towards high resolution portable applications is addressed. The various strategies for 1/f noise reduction and sensitivity enhancement in integrated GMR technology for sub-pT biomagnetic signal recording are discussed. In this paper, we review the developments of integrated GMR technology for in vivo/vitro biomagnetic source imaging and demonstrate how integrated GMR can be utilized for biomagnetic field detection. Since the field sensitivity of integrated GMR technology is being pushed to fT/Hz0.5 with the focused efforts, it is believed that the potential of integrated GMR technology will make it preferred choice in weak biomagnetic signal detection in the future.

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Giant Magnetoresistance (GMR) Materials and Devices for Biomedical and Industrial Applications

Saha

et al. 2022

Spintronics

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Microneedles with integrated magnetoresistive sensors: A precision tool in biomedical instrumentation

Cited by 8 publications

References 14 publications

Comparison of Sensitivity and Low-Frequency Noise Contributions in Giant-Magnetoresistive and Tunneling-Magnetoresistive Spin-Valve Sensors with a Vortex-State Free Layer

Comparison of Sensitivity and Low-Frequency Noise Contributions in Giant-Magnetoresistive and Tunneling-Magnetoresistive Spin-Valve Sensors with a Vortex-State Free Layer

Integrated Giant Magnetoresistance Technology for Approachable Weak Biomagnetic Signal Detections

Giant Magnetoresistance (GMR) Materials and Devices for Biomedical and Industrial Applications

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