Microneedles for Enhanced Bacterial Pathogen Inactivation and Accelerated Wound Healing
Akshay Krishnakumar,
Nicholas L.F. Gallina,
Devendra Sarnaik
et al.
Abstract:Bacterial wound infections are a significant socioeconomic concern in the modern healthcare industry owing to increased morbidity, prolonged hospital stay, and mortality. Bacterial infectious agents that colonize the wound bed develop biofilms, acting as a physical barrier that prevents the effective penetration of topical antimicrobials. Further, bacteria in such infectious wounds express a wide range of virulence factors promoting intercellular transmigration and host cell invasion complicating the treatment… Show more
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