Microneedles Based on a Biodegradable Polymer—Hyaluronic Acid
Jagoda Chudzińska,
Agata Wawrzyńczak,
Agnieszka Feliczak-Guzik
Abstract:Transdermal transport can be challenging due to the difficulty in diffusing active substances through the outermost layer of the epidermis, as the primary function of the skin is to protect against the entry of exogenous compounds into the body. In addition, penetration of the epidermis for substances hydrophilic in nature and particles larger than 500 Da is highly limited due to the physiological properties and non-polar nature of its outermost layer, namely the stratum corneum. A solution to this problem can… Show more
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