Microneedle System with Biomarker-Activatable Chromophore as Both Optical Imaging Probe and Anti-bacterial Agent for Combination Therapy of Bacterial-Infected Wounds and Outcome Monitoring
Juan Ouyang,
Lihe Sun,
Zunpan She
et al.
Abstract:Wounds infected with bacteria, if left untreated, have
the potential
to escalate into life-threatening conditions, such as sepsis, which
is characterized by widespread inflammation and organ damage. A comprehensive
approach to treating bacterial-infected wounds, encompassing the control
of bacterial infection, biofilm eradication, and inflammation regulation,
holds significant importance. Herein, a microneedle (MN) patch (FM@ST MN) has been developed, with silk fibroin (SF) and tannic
acid-based hydrogel servi… Show more
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