2015
DOI: 10.1364/oe.23.017156
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Micron scale directional coupler as a transducer for biochemical sensing

Abstract: A microfabricated directional coupler (DC) was used for the detection of DNA conjugated with quantum dots. Output optical signals from DCs of a wide range of device lengths correspond well to theoretical and simulation results. Even 20 µm-long DC devices could detect changes in the output optical intensity by monitoring the near-field pattern using a CCD camera. The signal was enhanced 60 × using a 1500 µm-long DC device. For large cladding refractive-index changes between air and water, the normalized signal … Show more

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Cited by 24 publications
(13 citation statements)
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“…Additional advantages by using polymers are the fabrication flexibility and the low power consumption [17,18]. These polymeric photonic sensors can be at the core of the innovative technology platform called photonic lab-on-a-chip (PhLOC) [7,19,20,21,22], aimed towards solving existing limitations in achieving low cost mass production devices for point-of-care diagnosis [23,24,25]. Even though the aim of the PhLOC is to integrate all the required elements—photonic and non-photonic—in a stand-alone system, there has been no demonstration that this configuration can achieve the claimed high sensitivity in a label-free evaluation [7,26].…”
Section: Introductionmentioning
confidence: 99%
“…Additional advantages by using polymers are the fabrication flexibility and the low power consumption [17,18]. These polymeric photonic sensors can be at the core of the innovative technology platform called photonic lab-on-a-chip (PhLOC) [7,19,20,21,22], aimed towards solving existing limitations in achieving low cost mass production devices for point-of-care diagnosis [23,24,25]. Even though the aim of the PhLOC is to integrate all the required elements—photonic and non-photonic—in a stand-alone system, there has been no demonstration that this configuration can achieve the claimed high sensitivity in a label-free evaluation [7,26].…”
Section: Introductionmentioning
confidence: 99%
“…Compared to out-of-plane configuration, in-plane configuration offers advantages such as on-chip integrability with light sources and detectors that can lead to better scalability, and larger optical path-to-cell volume ratio which will guarantee more compact sensors while maintaining high sensitivity [ 31 , 32 , 33 ]. Besides many demonstrations of different types of sensors relying on in-plane configuration, such as spiral waveguide sensors [ 34 , 35 , 36 ], ring/disk resonator sensors [ 37 , 38 ], slot waveguide sensors [ 39 , 40 , 41 ], and plasmonics based sensors [ 42 , 43 ], directional coupler (DC) as a key component for light routing and power splitting has also been explored as a nanophotonics sensor [ 44 , 45 ]. However, on the one hand, the operation bandwidth of these DC sensors is limited due to dispersion; on the other hand, a large footprint is required for the sensors to interact with the analyte in order to produce significant phase difference.…”
Section: Introductionmentioning
confidence: 99%
“…The refractive index change could be determined by measuring wavelength shift. Up to now, more and more optical fiber/waveguide devices have been utilized for detecting biochemical samples [6][7][8][9][10][11]. Among these devices, the structure comprising optical directional couplers is very attractive because it is easy to fabricate compact, well-performing and low-cost sensor to detect biochemical substances.…”
Section: Introductionmentioning
confidence: 99%