Microincineration of Active Smooth, Transitional and Skeletal Muscles.

Abstract

tion at 1 P.M. the next day, one dosis nf'cctarts of atabrine having been given at midnight between the 2 examinations. Twenty-two birds survived long enough to be included in tlie record of this investigation : controls were injected with water alone. 10559 Microincineration of Active Smooth, Transitional and SkeletalMuscles." * These investigations iwrc carried out with the aid of a grant for Research to tlir Departmmt of h a t o m y , Marquette Vnivrrsity School of Medicine, by the ('ommittee on Sc4entific. Research of the -4nierican Medical Association.

Electron Microscopic Observations on the Accumulation of Divalent Cations in Intramitochondrial Granules

“…Histochemical studies have also suggested a localization of calcium in mitochondria. Ash techniques (Scott, 1932;Carey and Zeit, 1939) have shown that calcium is localized in certain striated muscles in A and Z bands: this is the same as the distribution of mitochondria in these muscles (Bullard, 1912). Both ash and staining techniques were used by Reynolds (1960) to localize calcium, in liver cells of carbon tetrachloride-poisoned rats, to dense, granular masses that are, presumably, mitochondria.…”

Changes in Cardiac Contractility Evoked Under Isotonic and Isometric Conditions

“…The actual sites at whicb the proposed binding or accumulation of these ions takes place have not yet been identified but it should be recalled that the earlier micro-incineration studies of Scott (1932) and of Carey and Zeit (1939) revealed the presence of an ash in the A bands, along the surface of tlie fibres and along the fine transverse lines located in the position of the Z bands. This ash was that of a multivalent ion, presumably calcium and/or magnesium.…”