Microglia Signatures: A Cause or Consequence of Microglia-Related Brain Disorders?
Alessandra Mirarchi,
Elisabetta Albi,
Cataldo Arcuri
Abstract:Microglia signatures refer to distinct gene expression profiles or patterns of gene activity that are characteristic of microglia. Advances in gene expression profiling techniques, such as single-cell RNA sequencing, have allowed us to study microglia at a more detailed level and identify unique gene expression patterns that are associated, but not always, with different functional states of these cells. Microglial signatures depend on the developmental stage, brain region, and specific pathological conditions… Show more
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