Microfluidics in Microstructure Optical Fibers: Heat Flux and Pressure-driven and Other Flows

This article presents a diagnostic device model, which by using chemical reagents and microfluidics that makes a sort of particle separation and was developed to diagnose an acquired viral immunodeficiency. The device allows to isolate leukocytes and apply a reagent that measures the presence or absence of this virus. The design on the other hand uses tools such as SolidWorks and Autodesk Simulation, which, with the rupture of the membranes and the separation of their components, allows the chemical reaction in the particles and the detection of the virus. Based on the choice of particle analysis and validating the performance of the fluid maintained in the filter stage, which is represented by 5 flow lines, it shows the movement of 5 particles with the same diameter. Additionally, three tests were performed that varied the diameter of the particles to 5 μm, 10 μm and a larger diameter particle (15 μm). The results show that, with a diameter of 5 μm, the particles move smoothly and the filter can reach the next stage. The particles of 10 μm in diameter presented a normal blood flow, however, an obstruction in the particles of 15 μm in diameter can be observed.

show abstract

“…According to Christodoulies, et al (2014) [7], for small Knudsen numbers and considering a negligible gravity force in each microchannel, we get:…”

Section: Results and Analysismentioning

confidence: 98%

Design and simulation of microfluidic device for the detection of HIV

Lagos-Sandoval¹,

Salazar-Zuñiga²,

Berdugo-Romero³

2018

Vis. Electron.

View full text Add to dashboard Cite

show abstract

“…In this paper, finite element analysis (FEA) is used with the Navier-Stokes equations and the convection diffusion equations to investigate the influence of flow rates, fibre geometry and external temperature on a MOF. A schematic of the MOF studied is shown in Figure 1 and was chosen, since it built and expanded upon the work of Christodoulides et al [18]. Considering the optical properties, using the steady-state region of the MOF, the temperature change is converted into an equivalent change in refractive index, using the appropriate thermo-optic coefficients, where FEA is employed to calculate the bound modes of the MOF and their effective indices using the Helmholtz equation.…”

Section: Introductionmentioning

confidence: 99%

Microfluidic flow and heat transfer and their influence upon optical modes in microstructure fibres

Davies

Christodoulides

Florides

et al. 2015

Micro-Structured and Specialty Optical Fibres IV

View full text Add to dashboard Cite

Using finite element analysis (FEA), a model has been constructed to predict the thermo-fluidic and optical properties of a microstructure optical fibre (MOF). The properties under study include external temperature, input water velocity and optical fibre geometry. Under laminar flow the steady-state temperature is dependent on the water channel radius while independent of the input velocity. A critical channel radius is observed below which the steady-state temperature of the water channel is constant, while above, the temperature decreases. The MOF has been found capable of supporting multiple modes whose response to temperature was dominated by the thermo-optic coefficient of glass, despite the larger thermo-optic coefficient of water. This is attributed to the majority of the light being confined within the glass, which increased with increasing external temperature due to a larger difference in the refractive index between the glass core and the water channel.

show abstract

“…In this paper, finite element analysis (FEA) is used with the Navier–Stokes equations and the convection diffusion equations to investigate the influence of flow rates, fiber geometry and external temperature on a MOF. A schematic of the MOF studied is shown in Figure 1 and was chosen, since it built and expanded upon the work of Christodoulides et al [ 22 ]. Considering the optical properties, using the steady-state region of the MOF, the temperature change is converted into an equivalent change in refractive index, using the appropriate thermo-optic coefficients, where FEA is employed to calculate the bound modes of the MOF and their effective indices using the Helmholtz equation.…”

Section: Introductionmentioning

confidence: 99%

Microfluidic Flows and Heat Transfer and Their Influence on Optical Modes in Microstructure Fibers

et al. 2014

Self Cite

View full text Add to dashboard Cite

A finite element analysis (FEA) model has been constructed to predict the thermo-fluidic and optical properties of a microstructure optical fiber (MOF) accounting for changes in external temperature, input water velocity and optical fiber geometry. Modeling a water laminar flow within a water channel has shown that the steady-state temperature is dependent on the water channel radius while independent of the input velocity. There is a critical channel radius below which the steady-state temperature of the water channel is constant, while above, the temperature decreases. However, the distance required to reach steady state within the water channel is dependent on both the input velocity and the channel radius. The MOF has been found capable of supporting multiple modes. Despite the large thermo-optic coefficient of water, the bound modes’ response to temperature was dominated by the thermo-optic coefficient of glass. This is attributed to the majority of the light being confined within the glass, which increased with increasing external temperature due to a larger difference in the refractive index between the glass core and the water channel.

show abstract

Microfluidics in Microstructure Optical Fibers: Heat Flux and Pressure-driven and Other Flows

Cited by 4 publications

References 11 publications

Design and simulation of microfluidic device for the detection of HIV

Design and simulation of microfluidic device for the detection of HIV

Microfluidic flow and heat transfer and their influence upon optical modes in microstructure fibres

Microfluidic Flows and Heat Transfer and Their Influence on Optical Modes in Microstructure Fibers

Contact Info

Product

Resources

About