Microfluidics for personalized drug delivery

Alavi, Seyed Ebrahim; Alharthi, Sitah; Alavi, Seyedeh Fatemeh; Alavi, Seyed Zeinab; Zahra, Gull E.; Raza, Aun; Ebrahimi Shahmabadi, Hasan

doi:10.1016/j.drudis.2024.103936

Drug Discovery Today

2024

DOI: 10.1016/j.drudis.2024.103936

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Microfluidics for personalized drug delivery

Seyed Ebrahim Alavi,

Sitah Alharthi,

Seyedeh Fatemeh Alavi

et al.

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2024

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Cited by 5 publications

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Developing Engineered Nano-Immunopotentiators for the Stimulation of Dendritic Cells and Inhibition and Prevention of Melanoma

Alharthi,

Alavi,

Nisa

et al. 2024

Pharm Res

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Developing Engineered Nano-Immunopotentiators for the Stimulation of Dendritic Cells and Inhibition and Prevention of Melanoma

Alharthi,

Alavi,

Nisa

et al. 2024

Pharm Res

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Nanoparticle-integrated metal–organic frameworks: a revolution in next-generation drug delivery systems

Alavi,

Koohi

et al. 2024

J. Pharm. Investig.

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Background Nanometal-organic frameworks (nano-MOFs), which exhibit distinctive features, such as controlled release mechanisms, stimuli-responsive behaviors, and sustained drug release profiles, have emerged as promising candidates for next-generation drug delivery systems. Area covered This review outlines the impact of nano-MOFs in biomedical applications, emphasizing their potential for targeted drug delivery through active strategies and their biocompatibility considerations. Expert opinion The versatility and tunability of nano-MOFs pave the way for personalized medicine, allowing tailored formulations to meet individual patient needs. Despite their transformative potential, challenges remain in terms of stability, toxicity assessment, and standardization. As nano-MOFs progress from laboratory research to clinical trials, they present a paradigm shift in drug delivery, offering precision medicine solutions through theranostic platforms. The future holds promise for the use of nano-MOFs to revolutionize drug delivery, ushering in an era of personalized and effective therapeutic interventions.

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Synergistic strategies for enhanced liver cancer therapy with sorafenib/resveratrol PEGylated liposomes in vitro and in vivo

Alrashidi,

Alavi,

Koohi

et al. 2024

Journal of Drug Delivery Science and Technology

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Microfluidics for personalized drug delivery

Cited by 5 publications

References 104 publications

Developing Engineered Nano-Immunopotentiators for the Stimulation of Dendritic Cells and Inhibition and Prevention of Melanoma

Developing Engineered Nano-Immunopotentiators for the Stimulation of Dendritic Cells and Inhibition and Prevention of Melanoma

Nanoparticle-integrated metal–organic frameworks: a revolution in next-generation drug delivery systems

Synergistic strategies for enhanced liver cancer therapy with sorafenib/resveratrol PEGylated liposomes in vitro and in vivo

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