Microfluidics chip inspired by fish gills for blood cells and serum separation

DARBOUI, Milad; MOGHADAM, Reza ASKARI; Parichehr, Rasoul

doi:10.1016/j.sna.2022.113839

Cited by 8 publications

(6 citation statements)

References 39 publications

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“…CFM finds applications in various fields such as chemical separation, nanoparticle separation, particle focusing, and basic biochemical research. 159,160 4.1.2. Droplet microfluidics.…”

Section: Design Considerationsmentioning

confidence: 99%

“…It is primarily used for separation, such as separating blood into its different components based on physical or flow characteristics like acoustic, electrical, gravity, magnetic, thermal, or laser. 159 In a recent study, Bakhtairi et al utilized a Y-shaped microchannel in an automated microfluidic bead sorter capable of precisely positioning individual particles with an accuracy of tens of micrometres (Fig. 11b).…”

Section: Reviewmentioning

confidence: 99%

Section: Classificationmentioning

confidence: 99%

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Microfluidics: a concise review of the history, principles, design, applications, and future outlook

Hajam,

Khan

2024

Biomater. Sci.

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“…CFM finds applications in various fields such as chemical separation, nanoparticle separation, particle focusing, and basic biochemical research. 159,160 4.1.2. Droplet microfluidics.…”

Section: Design Considerationsmentioning

confidence: 99%

Section: Reviewmentioning

confidence: 99%

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Microfluidics: a concise review of the history, principles, design, applications, and future outlook

Hajam,

Khan

2024

Biomater. Sci.

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“…The cured PDMS is then removed from the mold and cut to the desired dimensions and shape. To ensure excellent adhesion and wetting of the PMDS, the receiving substrate is treated with a surface modifier, such as oxygen plasma treatment, UV/ozone treatment, chemical modification, or physical abrasion ( Long et al, 2017 ; Borók et al, 2021 ; Mondal et al, 2021 ; Darboui et al, 2022 ).…”

Section: Manufacturing Techniquesmentioning

confidence: 99%

Breaking the clean room barrier: exploring low-cost alternatives for microfluidic devices

Rodríguez

Andrade-Pérez

Vargas

et al. 2023

Front. Bioeng. Biotechnol.

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Microfluidics is an interdisciplinary field that encompasses both science and engineering, which aims to design and fabricate devices capable of manipulating extremely low volumes of fluids on a microscale level. The central objective of microfluidics is to provide high precision and accuracy while using minimal reagents and equipment. The benefits of this approach include greater control over experimental conditions, faster analysis, and improved experimental reproducibility. Microfluidic devices, also known as labs-on-a-chip (LOCs), have emerged as potential instruments for optimizing operations and decreasing costs in various of industries, including pharmaceutical, medical, food, and cosmetics. However, the high price of conventional prototypes for LOCs devices, generated in clean room facilities, has increased the demand for inexpensive alternatives. Polymers, paper, and hydrogels are some of the materials that can be utilized to create the inexpensive microfluidic devices covered in this article. In addition, we highlighted different manufacturing techniques, such as soft lithography, laser plotting, and 3D printing, that are suitable for creating LOCs. The selection of materials and fabrication techniques will depend on the specific requirements and applications of each individual LOC. This article aims to provide a comprehensive overview of the numerous alternatives for the development of low-cost LOCs to service industries such as pharmaceuticals, chemicals, food, and biomedicine.

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“…Filtration is the most common passive separation method, mainly including pillar-type and hole-type. [17][18][19] As the simplest method, filtration is widely used to separate various samples, but it often encounters the significant challenge of clogging. Secondary flow-based separation methods, particularly Dean flow, have been extensively studied on microfluidic chips.…”

Section: Introductionmentioning

confidence: 99%