Microfluidic Systems in Analytical Chemistry

Gómez‐Hens, A.; Fernández-Romero, J.M.

doi:10.1002/9780470027318.a9591

Cited by 6 publications

(3 citation statements)

References 109 publications

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“…The development of new designs and applications of microfluidic devices in recent decades is one of the most intensive directions of scientific research in analytical chemistry [86]. They are being developed both for fast single and multicomponent determinations based on CE separations [87], including programmable and reconfigurable chips [88] and paper-based microsystems [89].…”

Section: Simultaneous Determination Of Anions and Cationsmentioning

confidence: 99%

Application of Capillary Electrophoresis for Determination of Inorganic Analytes in Waters

Poboży

Trojanowicz

2021

Molecules

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Aside from HPLC and GC, capillary electrophoresis (CE) is one of the most important techniques for high-performance separations in modern analytical chemistry. Its main advantages are the possibility of using different detection techniques, the possibility of in-capillary sample processing for preconcentration or derivatization, and ease of instrumental miniaturization down to the microfluidic scale. Those features are utilized in the separation of macromolecules in biochemistry and in genetic investigations, but they can be also used in determinations of inorganic ions in water analysis. This review, based on about 100 original research works, presents applications of CE methods in water analysis reported in recent decade, mostly regarding conductivity detection or indirect UV detection. The developed applications include analysis of high salinity sea waters, as well as analysis of other surface waters and drinking waters.

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Section: Simultaneous Determination Of Anions and Cationsmentioning

confidence: 99%

Application of Capillary Electrophoresis for Determination of Inorganic Analytes in Waters

Poboży

Trojanowicz

2021

Molecules

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“…In our pursuit of fluorescent sensor development, various configurations have been explored [ 31 , 32 , 33 , 34 , 35 , 36 ]. Our long-standing approach involves combining a specific molecular fluorescent sensor with a microfluidic device, which has yielded successful results in previous studies targeting heavy metal detection (lead [ 37 ], mercury [ 38 ]).…”

Section: Introductionmentioning

confidence: 99%

A Highly Sensitive and Selective Optical Sensor for the On-Line Detection of Cesium in Water

Depauw,

Jonusauskaite,

Ghasemi

et al. 2023

Sensors

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In this study, we have undertaken the development of two fluorescent sensors based on calixarene compounds for the purpose of detecting cesium in water. By introducing the sulfonate functional groups, we have considerably improved the water solubility of sensors, enabling complete dissolution of products in aqueous media and direct analysis of polluted water samples. Through rigorous experiments, we have demonstrated that the complexation of Cs+ ions with sensors 1 and 2 in water leads to a remarkable enhancement of fluorescence. This fluorescence enhancement serves as a reliable indication of cesium presence and allows for sensitive detection. To further advance the practical application of our sensors, we have successfully integrated calixarene sensors 1 and 2 into a microfluidic sensor chip. This integration has enabled real-time, on-line measurements and has resulted in the development of a portable detection device capable of detecting cesium ions in water samples at parts per billion (ppb) levels. This device holds great promise for environmental monitoring and assessment, providing a convenient and efficient solution for cesium detection. Our work represents a significant advancement in the field of cesium detection, displaying the efficacy of calixarene-based fluorescent sensors and their integration into microfluidic systems. The enhanced water solubility, fluorescence response, and portability of our detection device offers tremendous potential for applications in environmental monitoring, water quality assessment, and emergency response scenarios where rapid and accurate cesium detection is crucial.

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“…29 With unique advantages, microfluidic devices have found successful applications in a wide range of fields such as synthetic and analytical chemistry, biology, biomedical research, point-of-care diagnostics, drug discovery, and healthcare. 30–37…”

Section: Introductionmentioning

confidence: 99%