2011
DOI: 10.1038/ncomms1471
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Microfluidic quadrupole and floating concentration gradient

Abstract: The concept of fluidic multipoles, in analogy to electrostatics, has long been known as a particular class of solutions of the Navier-Stokes equation in potential flows, however, experimental observations of fluidic multipoles and of their characteristics have not been reported yet. Here we present a two-dimensional microfluidic quadrupole and a theoretical analysis consistent with the experimental observations. The microfluidic quadrupole was formed by simultaneously injecting and aspirating fluids from two p… Show more

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Cited by 89 publications
(102 citation statements)
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“…The theoretical understanding of the properties of hydrodynamically confined flows is still far from complete, even though the flow confinement for two channel geometries in close proximity to a surface are well described, and experimentally validated modeling studies have recently appeared [22,31]. This includes investigations of the influence of geometry, flow rate and other parameters on device performance.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The theoretical understanding of the properties of hydrodynamically confined flows is still far from complete, even though the flow confinement for two channel geometries in close proximity to a surface are well described, and experimentally validated modeling studies have recently appeared [22,31]. This includes investigations of the influence of geometry, flow rate and other parameters on device performance.…”
Section: Discussionmentioning
confidence: 99%
“…Arrays of several channels are not more difficult to produce. A variant of this device with a planar 2 × 2 channel array was later utilized to investigate the concept of fluidic multipoles [31].…”
Section: The Microfluidic Probementioning
confidence: 99%
“…The mass diffusivity of uranine is 0.50 Â 10 À3 mm 2 /s, which is given in Ref. [16]. The calculation results, shown by the concentration profiles in Fig.…”
Section: Numerical Simulation Of Mass Transfer Including Chemical Reamentioning
confidence: 99%
“…ranging from fabrication of tissue structures167 and biological assays 168 to single-cell analysis 169. In particular, microfluidic technologies offer an interesting approach for creating functional hydrogels with 3D morphologies and tunable chemicalstructures.…”
mentioning
confidence: 99%