Microfluidic production of monodisperse emulsions for cosmetics

Park, Dae-Hwan; Kim, Ha-Jeong; Kim, Jinwoong

doi:10.1063/5.0057733

Cited by 19 publications

(11 citation statements)

References 84 publications

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“…The yield in the final step was 68%. The structure was confirmed by 1 H NMR (500 MHz, DMSO-d 6 ) 7.81 (dd, J = 9.0, 3.2 Hz, 4H), 7.10 (dd, J = 8.9, 4.3 Hz, 4H), 4.07 (dt, J = 9.0, 6.5 Hz, 4H), 3.54 (t, J = 6.7 Hz, 2H), 3.30-3.22 (m, 10H), 3.18-3.07 (m, 5H), 1.85-1.70 (m, 6H), 1.62 (qd, J = 7.2, 3.9 Hz, 3H), 1.52-1.33 (m, 10H), 1.17 (tt, J = 7.3, 1.8 Hz, 14H). The corresponding NMR spectrum is given in the ESI † (Fig.…”

Section: Synthesis Of Light-active Bolaform Surfactants (Labss)mentioning

confidence: 77%

“…Emulsions stabilised by surfactants and particles are of technological importance in cosmetics, food processing and paints. [1][2][3] In these applications, the stability of emulsions determines the quality of the product, and hence it is necessary to ensure prevention of phase-separation. However, undesirable and inevitable formation of emulsions poses challenges in enhanced crude oil recovery, 4 lipid extraction from microalgae, 5 oil spilling in the ocean etc.…”

Section: Introductionmentioning

confidence: 99%

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Light-induced destabilisation of oil-in-water emulsions using light-active bolaform surfactants

et al. 2023

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Section: Synthesis Of Light-active Bolaform Surfactants (Labss)mentioning

confidence: 77%

Section: Introductionmentioning

confidence: 99%

Light-induced destabilisation of oil-in-water emulsions using light-active bolaform surfactants

et al. 2023

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“…Mastering the dynamics of dispersed micro-objects, such as beads, drops or bubbles transported by an external flow, is crucial in many situations, including (i) the control and optimization of two-phase flows through porous materials for the food, pharmaceutical or cosmetic industries (Muschiolik 2007;Park, Kim & Kim 2021), (ii) the improvement of heat and mass transfer or the intensification of heterogeneous reactions for energy or chemical applications (Song, Chen & Ismagilov 2006), (iii) the enhanced recovery of residual oils in the petroleum industry (Green & Willhite 1998) and (iv) biomedical and biological applications where these objects represent model systems for cell sorting (Hur et al 2011b;Chen et al 2014).…”

Section: Introductionmentioning

confidence: 99%

Beads, bubbles and drops in microchannels: stability of centred position and equilibrium velocity

et al. 2023

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Understanding and predicting the dynamics of dispersed micro-objects in microfluidics is crucial in numerous natural, industrial and technological situations. In this paper, we experimentally characterized the equilibrium velocity $V$ and lateral position $\varepsilon$ of various dispersed micro-objects, such as beads, bubbles and drops, in a cylindrical microchannel over an unprecedentedly wide range of parameters. By varying the dimensionless object size ( $d \in [0.1; 1]$ ), the viscosity ratio ( $\lambda \in [10^{-2}; \infty [$ ), the density ratio ( $\varphi \in [10^{-3}; 2]$ ), the Reynolds number ( $Re \in [10^{-2}; 10^2]$ ) and the capillary number ( $Ca \in [10^{-3}; 0.3]$ ), we offer an exhaustive parametric study exploring various dynamics from the non-deformable viscous regime to the deformable inertial regime, thus enabling us to highlight the sole and combined roles of inertia and capillary effects on lateral migration. Experiments are compared and agree well with a steady three-dimensional Navier–Stokes model for incompressible two-phase fluids, including the effects of inertia and possible interfacial deformations. This model enables us to propose a correlation for the object velocity $V$ as functions of $d$ , $\varepsilon$ and $\lambda$ , obtained in the ${Re}={Ca}=0$ limit, but valid for a larger range of values of ${Re}$ and ${Ca}$ delimited by the validity of the linear regime. Next, we present stability maps for the centred position showing that non-deformable objects dominated by inertial effects are only stable if large enough, typically for $d \gtrsim 0.7$ , whereas deformable objects dominated by capillary effects can be stable for much smaller sizes, provided the viscosity ratio is outside the range $0.7 \lesssim \lambda \lesssim 10$ , in which deformability also plays a destabilizing effect, as for inertia.

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“…Microfluidic channels are widely used to produce droplets with controlled size and low polydispersity index, which are important in applications such as emulsification, inkjet printing, cosmetics and healthcare (Lawrence & Rees 2000; Yang et al. 2018; Park, Kim & Kim 2021). Surfactants are commonly added during drop formation to modify the interfacial properties and improve the stability of the emulsions.…”

Section: Introductionmentioning

confidence: 99%

Effect of surfactants during drop formation in a microfluidic channel: a combined experimental and computational fluid dynamics approach

et al. 2023

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The effect of surfactants on the flow characteristics during rapid drop formation in a microchannel is investigated using high-speed imaging, micro-particle image velocimetry and numerical simulations; the latter are performed using a three- dimensional multiphase solver that accounts for the transport of soluble surfactants in the bulk and at the interface. Drops are generated in a flow-focusing microchannel, using silicone oil ( $4.6$ mPa s) as the continuous phase and a 52 % w/w glycerol solution as the dispersed phase. A non-ionic surfactant (Triton X-100) is dissolved in the dispersed phase at concentrations below and above the critical micelle concentration. Good agreement is found between experimental and numerical data for the drop size, drop formation time and circulation patterns. The results reveal strong circulation patterns in the forming drop in the absence of surfactants, whose intensity decreases with increasing surfactant concentration. The surfactant concentration profiles in the bulk and at the interface are shown for all stages of drop formation. The surfactant interfacial concentration is large at the front and the back of the forming drop, while the neck region is almost surfactant free. Marangoni stresses develop away from the neck, contributing to changes in the velocity profile inside the drop.

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Microfluidic production of monodisperse emulsions for cosmetics

Cited by 19 publications

References 84 publications

Light-induced destabilisation of oil-in-water emulsions using light-active bolaform surfactants

Light-induced destabilisation of oil-in-water emulsions using light-active bolaform surfactants

Beads, bubbles and drops in microchannels: stability of centred position and equilibrium velocity

Effect of surfactants during drop formation in a microfluidic channel: a combined experimental and computational fluid dynamics approach

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