Microfluidic platform for omics analysis on single cells with diverse morphology and size: A review

Lin, Shujin; Feng, Dan; Han, Xiao; Li, Ling; Lin, Yao; Gao, Haibing

doi:10.1016/j.aca.2024.342217

Analytica Chimica Acta

2024

DOI: 10.1016/j.aca.2024.342217

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Microfluidic platform for omics analysis on single cells with diverse morphology and size: A review

Shujin Lin,

Dan Feng,

Xiao Han

et al.

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Cited by 2 publications

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Atypical applications of transverse diffusion of laminar flow profiles methodology for in‐capillary reactions in capillary electrophoresis

Bržezická,

Kohútová,

Glatz

2024

J of Separation Science

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Capillary electrophoresis (CE) is a powerful separation technique offering quick and efficient analyses in various fields of bioanalytical chemistry. It is characterized by many well‐known advantages, but one, which is perhaps the most important for this application field, is somewhat overlooked. It is the possibility to perform chemical and biochemical reactions at the nL scale inside the separation capillary. There are two basic formats applicable for this purpose, heterogeneous and homogeneous. In the former, one reactant is immobilized onto a particle or monolithic support or directly on the capillary wall, and the other is injected. In the latter, the reactant mixing inside a capillary is based on electromigration or diffusion. One of the diffusion‐based methodologies, termed Transverse Diffusion of Laminar Flow Profiles, is the subject of this review. Since most studies utilizing in‐capillary reactions in CE focus on enzymes, which are being continuously and exhaustively reviewed, this review covers the atypical applications of this methodology, but still in the bioanalytical field. As can be seen from the demonstrated applications, they are not limited to reactions, but can also be utilized for other biochemical systems.

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Atypical applications of transverse diffusion of laminar flow profiles methodology for in‐capillary reactions in capillary electrophoresis

Bržezická,

Kohútová,

Glatz

2024

J of Separation Science

View full text Add to dashboard Cite

show abstract

Open and closed microfluidics for biosensing

Ge,

Hu,

Zhang

et al. 2024

Materials Today Bio

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Microfluidic platform for omics analysis on single cells with diverse morphology and size: A review

Cited by 2 publications

References 206 publications

Atypical applications of transverse diffusion of laminar flow profiles methodology for in‐capillary reactions in capillary electrophoresis

Atypical applications of transverse diffusion of laminar flow profiles methodology for in‐capillary reactions in capillary electrophoresis

Open and closed microfluidics for biosensing

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