Microfluidic paper-based chip platform for benzoic acid detection in food

Liu, Chan Chiung; Wang, Yao Nan; Fu, Lung-Ming; Chen, Kuan‐Lin

doi:10.1016/j.foodchem.2018.01.004

Cited by 84 publications

(21 citation statements)

References 38 publications

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“… Target analyte Matrix Sensor type Performed image analysis Optimum space Hardware Software # Phones Ref Escherichia coli and Enterococcus species lettuce liquid assay (enzymatic substrate conversion) grayscale intensity from B NC box and flashlight (flash adapted) ImageJ, no app 1 [ 35 ] mercury (II) tap water, serum nanosheet with nanozyme activity (TMB conversion) various RGB ratios (G + B)/2R no hardware, flash not specified commercial App (colour assist) 1 [ 55 ] iron meat and liver chromogenic assays (1,10-phenanthroline, 2,4,6-tris(2-pyridyl)-striazine, salicylate) for iron ions RGB, Hunter-LAB, CIE-Lab, CIE-Luv, CIE-LCh, HSV, HSL ΔELab and ΔELuv ΔELab and ΔELuv box, white paper used as diffuser. Illumination with TL lamp ImageJ, no app 1 [ 32 ] benzoic acid 21 commercial food samples μPAD using Janovsky reaction sum of R and B channels NC box with LED and CMOS camera and additional hardware in-house developed app 1 [ 56 ] gluten, cow milk, pH milk, cheese, soil lateral flow devices, ELISA, nanoparticles on filterpaper channels of RGB, HSV, LAB and weighed RGB R, G or B (depending assay) no hardware compared with box, flash used commercial app (RGB android) 6 [ 25 ] mercury ions, ochratoxin A and Salmonella tap water upconversion nanoparticle functionalised aptamers in lateral flow device grey scale intensity of separate RGB channels NC 3D box with LED array, lens, dichroic mirror ImageJ, no app 1 [ …”

Section: Hardware/software Development and Image Analysis Proceduresmentioning

confidence: 99%

Smartphone-based optical assays in the food safety field

Nelis

Tsagkaris

Dillon

et al. 2020

TrAC Trends in Analytical Chemistry

114

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Smartphone based devices (SBDs) have the potential to revolutionize food safety control by empowering citizens to perform screening tests. To achieve this, it is of paramount importance to understand current research efforts and identify key technology gaps. Therefore, a systematic review of optical SBDs in the food safety sector was performed. An overview of reviewed SBDs is given focusing on performance characteristics as well as image analysis procedures. The state-of-the-art on commercially available SBDs is also provided. This analysis revealed several important technology gaps, the most prominent of which are: (i) the need to reach a consensus regarding optimal image analysis, (ii) the need to assess the effect of measurement variation caused by using different smartphones and (iii) the need to standardize validation procedures to obtain robust data. Addressing these issues will drive the development of SBDs and potentially unlock their massive potential for citizen-based food control.

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Section: Hardware/software Development and Image Analysis Proceduresmentioning

confidence: 99%

Smartphone-based optical assays in the food safety field

Nelis

Tsagkaris

Dillon

et al. 2020

TrAC Trends in Analytical Chemistry

114

View full text Add to dashboard Cite

show abstract

“…The colour change of paper substrate was detectable by the naked eye, indicating the presence of target pathogen. Besides pathogen detection, μPAD has also been fabricated for the colorimetric detection of food chemicals such as nitrite ions [38], benzoic acid [39] and copper ions [40] in food and water, which is simple and cost-effective, and it can be operated by the untrained users, highlighting its significant use for rapid food safety monitoring.…”

Section: Recent Advances Of Poc Diagnostic Techniques For Food Safmentioning

confidence: 99%

Emerging Point-of-care Technologies for Food Safety Analysis

Choi

Yong

Choi

et al. 2019

Sensors

126

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Food safety issues have recently attracted public concern. The deleterious effects of compromised food safety on health have rendered food safety analysis an approach of paramount importance. While conventional techniques such as high-performance liquid chromatography and mass spectrometry have traditionally been utilized for the detection of food contaminants, they are relatively expensive, time-consuming and labor intensive, impeding their use for point-of-care (POC) applications. In addition, accessibility of these tests is limited in developing countries where food-related illnesses are prevalent. There is, therefore, an urgent need to develop simple and robust diagnostic POC devices. POC devices, including paper- and chip-based devices, are typically rapid, cost-effective and user-friendly, offering a tremendous potential for rapid food safety analysis at POC settings. Herein, we discuss the most recent advances in the development of emerging POC devices for food safety analysis. We first provide an overview of common food safety issues and the existing techniques for detecting food contaminants such as foodborne pathogens, chemicals, allergens, and toxins. The importance of rapid food safety analysis along with the beneficial use of miniaturized POC devices are subsequently reviewed. Finally, the existing challenges and future perspectives of developing the miniaturized POC devices for food safety monitoring are briefly discussed.

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“…Liu et al [93] proposed an integrated microfluidic platform based on the Janovsky reaction theory, which consists of a microfluidic paper-based analysis device (PAD) and a portable benzoic acid concentration detection system. The 3,5-dinitrobenzoic acid obtained by the reaction of benzoic acid sample with KNO 3 and H 2 SO 4 was dropped in the reaction zone of the chip.…”

Section: Detection Of Food Additivesmentioning

confidence: 99%

Application of Microfluidic Chip Technology in Food Safety Sensing

Gao

Yan

et al. 2020

Sensors

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Food safety analysis is an important procedure to control food contamination and supervision. It is urgently needed to construct effective methods for on-site, fast, accurate and popular food safety sensing. Among them, microfluidic chip technology exhibits distinguish advantages in detection, including less sample consumption, fast detection, simple operation, multi-functional integration, small size, multiplex detection and portability. In this review, we introduce the classification, material, processing and application of the microfluidic chip in food safety sensing, in order to provide a good guide for food safety monitoring.

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Microfluidic paper-based chip platform for benzoic acid detection in food

Cited by 84 publications

References 38 publications

Smartphone-based optical assays in the food safety field

Smartphone-based optical assays in the food safety field

Emerging Point-of-care Technologies for Food Safety Analysis

Application of Microfluidic Chip Technology in Food Safety Sensing

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