Microfluidic colorimetric analysis system for sodium benzoate detection in foods

Cui

et al. 2022

J. Agric. Food Chem.

Food safety is an issue that cannot be ignored at any time because of the great impact of food contaminants on people's daily life, social production, and the economy. Because of the extensive demand for high-quality food, it is necessary to develop rapid, reliable, and efficient devices for food contaminant detection. Microfluidic paper-based analytical devices (μPADs) have been applied in a variety of detection fields owing to the advantages of low-cost, ease of handling, and portability. This review systematically discusses the latest progress of μPADs, including the fundamentals of fabrication as well as applications in the detection of chemical and biological hazards in foods, hoping to provide suitable screening strategies for contaminants in foods and accelerating the technology transformation of μPADs from the lab into the field.

Section: Application Of μPads In the Detection Of Chemical Hazards In...mentioning

confidence: 99%

Section: ■ Overview Of μPadsmentioning

confidence: 99%

Microfluidic Paper-Based Analytical Devices for the Determination of Food Contaminants: Developments and Applications

Cui

et al. 2022

J. Agric. Food Chem.

“… 13 Very recently, the employment of a microfluidic colorimetric analysis system for detecting sodium benzoate was presented, where the involved colour variation was modelled with linear expression with respect to the analyte concentration featuring the sound determination coefficient of R 2 = 0.997. 14 Unfortunately, it was necessary for the colorimetric reaction to be initiated at 120 °C, which is a major disadvantage for its practical utilization.…”

Section: Introductionmentioning

confidence: 99%

Unveiling the detection kinetics and quantitative analysis of colorimetric sensing for sodium salts using surface-modified Au-nanoparticle probes

Hsiao

Chen

et al. 2022

Nanoscale Adv.

“…Paper-based analytical devices (μPADs) have a high integration capability and good biocompatibility and have found extensive utilization in various fields in the recent years, such as biomedicine, environmental monitoring, food science, pharmaceuticals, drug development, and more [ 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 ]. In clinical applications, paper-based devices have many advantages over the benchtop techniques described above, including a significantly lower cost, faster throughput, simpler operation, lower reagent consumption, and greater portability [ 59 , 60 , 61 , 62 ].…”

Section: Introductionmentioning

confidence: 99%

Microfluidic Sliding Paper-Based Device for Point-of-Care Determination of Albumin-to-Creatine Ratio in Human Urine

et al. 2022

Self Cite

A novel assay platform consisting of a microfluidic sliding double-track paper-based chip and a hand-held Raspberry Pi detection system is proposed for determining the albumin-to-creatine ratio (ACR) in human urine. It is a clinically important parameter and can be used for the early detection of related diseases, such as renal insufficiency. In the proposed method, the sliding layer of the microchip is applied and the sample diffuses through two parallel filtration channels to the reaction/detection areas of the microchip to complete the detection reaction, which is a simple method well suited for self-diagnosis of ACR index in human urine. The RGB (red, green, and blue) value intensity signals of the reaction complexes in these two reaction zones are analyzed by a Raspberry Pi computer to derive the ACR value (ALB and CRE concentrations). It is shown that the G + B value intensity signal is linearly related to the ALB and CRE concentrations with the correlation coefficients of R2 = 0.9919 and R2 = 0.9923, respectively. It is additionally shown that the ALB and CRE concentration results determined using the proposed method for 23 urine samples were collected from real suffering chronic kidney disease (CKD) patients are in fine agreement with those acquired operating a traditional high-reliability macroscale method. Overall, for point-of-care (POC) CKD diagnosis and monitoring in clinical applications, the results prove that the proposed method offers a convenient, real time, reliable, and low-spending solution for POC CKD diagnosis.