Microfluidic chip designs process optimization and dimensional quality control

Calaon, Matteo; Hansen, Hans Nørgaard; Tosello, Guido; Garnæs, Jørgen; Nørregaard, Jesper; Li, Wei

doi:10.1007/s00542-013-2025-3

Cited by 20 publications

(23 citation statements)

References 13 publications

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“…Nano channels gratings were defined as finger print test structures and molded on Cyclic Olefin Copolymer (COC) Topas 5013 L10. The injection molding process setting levels demonstrated in [10] to improve the replication quality of produced sub-micrometer geometries was used as starting point to define the new optimal process windows used during the molding experiments presented in this work. Replication fidelity between master and polymer geometries produced by conventional IM and ICM was quantified in terms of dimensional deviation from the corresponding nickel nano features.…”

Section: Introductionmentioning

confidence: 99%

Injection and injection-compression moulding replication capability for the production of polymer lab-on-a-chip with nano structures

Calaon

Tosello

Garnæs

et al. 2017

J. Micromech. Microeng.

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Section: Introductionmentioning

confidence: 99%

Injection and injection-compression moulding replication capability for the production of polymer lab-on-a-chip with nano structures

Calaon

Tosello

Garnæs

et al. 2017

J. Micromech. Microeng.

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“…Micro- and nanocrosses were produced following a procedure reported elsewhere [37]. Each wing of the microfeatures is 5 µm in height and 20 µm in width.…”

Section: Methodsmentioning

confidence: 99%

Replication of Micro- and Nanofeatures in Injection Molding of Two PLA Grades with Rapid Surface-Temperature Modulation

2018

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The production by injection molding of polymeric components having micro- and nanometrical surfaces is a complex task. Generally, the accurate replication of micro- and nanometrical features on the polymeric surface during the injection-molding process is prevented by of the low mold temperature adopted to reduce cooling time. In this work, we adopt a system that allows fast heating of the cavity surface during the time the melt reaches the cavity, and fast cooling after heater deactivation. A nickel insert with micro- and nanofeatures in relief is located on the cavity surface. Replication accuracy is analyzed by Atomic Force Microscopy under different injection-molding conditions. Two grades of polylactic acid with different viscosity have been adopted. The results indicate that the higher the cavity surface temperature is, the higher the replication accuracy is. The viscosity has a significant effect only in the replication of the microfeatures, whereas its effect results are negligible in the replication of nanofeatures, thus suggesting that the interfacial phenomena are more important for replication at a nanometric scale. The evolution of the crystallinity degree on the surface also results in a key factor on the replication of nanofeatures.

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“…The nano and micro-features produced for this work were created on nickel shim insert; the procedure for fabricating the master geometry is reported elsewhere (Calaon et al, 2013;Menotti et al, 2014). As shown in Figure 1 The mold contained a rectangular cavity with a length of 110 mm, width of 12.7 mm, and thickness of 1.5 mm; the gate had a thickness of 0.5 mm ( Figure 2).…”

Section: Methodsmentioning

confidence: 99%

“…Some methods to reduce the effect due to the interaction between the tip and the sample are reported in the literature (Calaon et al, 2013). In this paper, to reduce the effect due to asymmetry of the tip, two acquisitions were performed for each sample, rotating the sample of 180° after the first acquisition.…”

Section: Accepted Manuscriptmentioning

confidence: 99%

“…A different replication index was adopted with nano-features. In particular, the nano-feature height, h, was adopted in these cases, as already proposed in literature (Calaon et al, 2013). The percentage deviation of the feature height (h), measured on the features replicated on the molded sample, from the height of the nickel insert (60±3 nm) was indicated as H, according to equation (2).…”

Section: Accepted Manuscriptmentioning

confidence: 99%

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Replication of micro and nano-features on iPP by injection molding with fast cavity surface temperature evolution

et al. 2017

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Microfluidic chip designs process optimization and dimensional quality control

Cited by 20 publications

References 13 publications

Injection and injection-compression moulding replication capability for the production of polymer lab-on-a-chip with nano structures

Injection and injection-compression moulding replication capability for the production of polymer lab-on-a-chip with nano structures

Replication of Micro- and Nanofeatures in Injection Molding of Two PLA Grades with Rapid Surface-Temperature Modulation

Replication of micro and nano-features on iPP by injection molding with fast cavity surface temperature evolution

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