“…Several works have demonstrated that higher IDEA thickness or height of the electrodes results in higher redox amplification factors [ 49 , 54 , 126 , 127 ]. In addition, increasing the surface area of IDEA-based sensors can be achieved in various ways, such as by fabricating pillars on top of the 2D IDEAs [ 128 , 129 ], by controlling the spin-coated thickness and shape of the photoresist carbon precursor material [ 54 , 130 , 131 , 132 , 133 , 134 ], and by growing vertically aligned carbon nanotubes (VACNT) on top of planar IDEA [ 135 , 136 ]. Interestingly, without increasing the extent of the IDEA’s thickness, the integrated microchannel [ 121 , 137 , 138 ] and combination with a mesh [ 139 ] on IDEAs does improve the amplification factor due to the large surface area of the redox cycling event.…”