Microfabricated porous layer open tubular (PLOT) column

Li, Maxwell Wei-Hao; She, Jinyan; Zhu, H.; Li, Ziqi; Fan, Xudong

doi:10.1039/c9lc00886a

Cited by 8 publications

(3 citation statements)

References 38 publications

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“…Finally, we investigated a possibility of using the nanowire microtubes as a separation medium in liquid chromatography (LC). In general, particle-packed or monolithic columns are employed in liquid-phase separations. − Open tubular columns can be used only in gas chromatography and microfluidics , because the molecular diffusion is not enough in liquid-phase separations. The achievement of an effective liquid-phase separation with an open tubular column provides ultralow-pressure analysis, such as in LC.…”

Section: Introductionmentioning

confidence: 99%

Rational Strategy for Space-Confined Seeded Growth of ZnO Nanowires in Meter-Long Microtubes

Kamei

Hosomi

Kanao

et al. 2021

ACS Appl. Mater. Interfaces

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Seeded crystal growths of nanostructures within confined spaces offer an interesting approach to design chemical reaction spaces with tailored inner surface properties. However, such crystal growth within confined spaces tends to be inherently difficult as the length increases as a result of confinement effects. Here, we demonstrate a space-confined seeded growth of ZnO nanowires within meter-long microtubes of 100 μm inner diameter with the aspect ratio of up to 10 000, which had been unattainable to previous methods of seeded crystal growths. ZnO nanowires could be grown via seeded hydrothermal crystal growth for relatively short microtubes below the length of 40 mm, while any ZnO nanostructures were not observable at all for longer microtubes above 60 mm with the aspect ratio of 600. Microstructural and mass spectrometric analysis revealed that a conventional seed layer formation using zinc acetate is unfeasible within the confined space of long microtubes as a result of the formation of detrimental residual Zn complex compounds. To overcome this space-confined issue, a flow-assisted seed layer formation is proposed. This flow-assisted method enables growth of spatially uniform ZnO nanowires via removing residual compounds even for 1 m long microtubes with the aspect ratio of up to 10 000. Finally, the applicably of ZnO-nanowire-decorated long microtubes for liquid-phase separations was demonstrated.

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Section: Introductionmentioning

confidence: 99%

Rational Strategy for Space-Confined Seeded Growth of ZnO Nanowires in Meter-Long Microtubes

Kamei

Hosomi

Kanao

et al. 2021

ACS Appl. Mater. Interfaces

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“…Microfabricated GC columns at the University of Michigan began in the laboratory of Richard Sacks . Further developments of microfabricated GC columns have continued in the laboratories of Katsuo Kurabayashi and Xudong Fan. − These systems have extended to different detectors, − multidimensional micro GC–GC systems (two-dimensional (2D) and three-dimensional (3D) systems), microinjectors (preconcentrators), , and micro thermal modulators . We have previously demonstrated the analytical utility of multidimensional gas chromatography for in situ investigations of multiple harsh environments. , In this paper, work focuses on an adaptation for GC–MS of a MEMS micro GC equipped with a 10 m long rectangular (150 μm × 240 μm) analytical column and micro-photoionization detector (μ-PID) at the GC analytical column exit.…”

Section: Introductionmentioning

confidence: 99%

Experimental Coupling of a MEMS Gas Chromatograph and a Mass Spectrometer for Organic Analysis in Space Environments

Libardoni

Miller

et al. 2020

ACS Earth Space Chem.

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The mass spectrometer for planetary exploration (MASPEX) is a versatile mass spectrometer with unprecedented mass resolution designed for spaceflight. However, the current version of MASPEX is designed for continuous sampling during flybys of planetary bodies and does not include gas chromatography, which can improve the analysis of complex mixtures of organic compounds in space environments. Here, micro-electro-mechanical system (MEMS) gas chromatography (GC) linearity, reproducibility, and column analytical performance were first demonstrated prior to the coupling to MASPEX for MEMS GC−mass spectrometer (MS) analyses. Linearity of response was demonstrated for n-hexane over 2 orders of magnitude of on-column mass (concentration). Retention time reproducibility in the MEMS GC was ≤2% relative standard deviation (RSD). MEMS GC column analytical performance calculations showed the average number of theoretical plates, N, and the height equivalent to a theoretical plate, HETP, to be 16 239 (1623 plates per meter) and 0.062 cm, respectively. N defines a chromatographic centroid peak apex divided by the peak width at half height, similar to mass resolution. When coupled to MASPEX, the retention time reproducibility was in a similar range of 1−2% relative standard deviation with a slightly larger deviation seen from the mass spectrometer detector due to start trigger variations with a manual start trigger in the FastFlight software compared to the LabView code used for the MEMS GC−MS testing. The collected mass spectra showed close consistency with National Institute of Standards and Technology (NIST) reference mass spectra providing confidence in chemical compound identification. We present the first data generated from the coupling of these devices.

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“…Recent studies have proposed to fabricate microcolumns with round channels so the pooling effect is reduced/eliminated. [183] Other possible routes of obtaining a uniform coating involve micro-engineered deposition of very thin layer, for example use of mono-layer gold as stationary phase, [348] the use of an intermediate aluminum oxide layer for ionic liquid coating [259] or the use of plasma-enhanced-chemical-vapor-deposition (PECVD) to deposit a thin porous SiOCH as a stationary phase. [262] Possibly, the use of an intermediate support layer to round off the sharp corners, prior to the actual stationary phase coating, could alleviate the pooling problem.…”

Section: Micro-fabrication and Testing Of A Radially Elongated Pillar...mentioning

confidence: 99%

Extending the microfabrication and particle handling toolbox for the development of ordered chromatography columns

Verloy

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be reproduced, stored in a retrieval system or transmitted in any form or by any means without permission of the author. Alle rechten voorbehouden. Niets uit deze uitgave mag worden vermenigvuldigd, in enige vorm of op enige wijze, zonder voorafgaande schriftelijke toestemming van de auteur. EXTENDING THE MICROFABRICATION AND PARTICLE HANDLING TOOLBOX FOR THE DEVELOPMENT OF ORDERED CHROMATOGRAPHY COLUMNS DISSERTATION to obtain the degree of doctor at the University of Twente, on the authority of the rector magnificus, prof. dr. ir. A. Veldkamp, on account of the decision of the Doctorate Board to be publicly defended on Thursday, 2 June 2022 at 16.45 hours by Sandrien Verloy born on

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Microfabricated porous layer open tubular (PLOT) column

Abstract: Development of a porous layer open tubular micro-column for light volatiles analysis enables broader micro-gas chromatography applicability to on-site environmental protection, industrial monitoring, and toxicology.

Cited by 8 publications

References 38 publications

Rational Strategy for Space-Confined Seeded Growth of ZnO Nanowires in Meter-Long Microtubes

Rational Strategy for Space-Confined Seeded Growth of ZnO Nanowires in Meter-Long Microtubes

Experimental Coupling of a MEMS Gas Chromatograph and a Mass Spectrometer for Organic Analysis in Space Environments

Extending the microfabrication and particle handling toolbox for the development of ordered chromatography columns

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