Microencapsulation structures based on protein-coated liposomes obtained through electrospraying for the stabilization and improved bioaccessibility of curcumin

Gómez‐Mascaraque, Laura G.; Sípoli, Caroline Casagrande; Torre, Lucimara Gaziola de la; López‐Rubio, Amparo

doi:10.1016/j.foodchem.2017.04.133

Cited by 106 publications

(47 citation statements)

References 42 publications

(42 reference statements)

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“…The microparticles obtained were spherical with a diameter of nearly 1 µm. This study showed that whey-protein microparticles can protect curcumin from degradation in PBS buffer (pH 7.4) and curcumin-liposome digestion in the gastrointestinal environment [162]. Jyoti et al synthesized curcumin complexed with 2-hydroxylpropyl-β-cyclodextrin loaded in chitosan microspheres by the emulsion-polymerization technique.…”

Section: Microcarriers For Curcumin Deliverymentioning

confidence: 97%

Improvement of Curcumin Bioavailability for Medical Applications

Her¹,

Venier-Julienne²,

Roger³

2018

Med Aromat Plants

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Section: Microcarriers For Curcumin Deliverymentioning

confidence: 97%

Improvement of Curcumin Bioavailability for Medical Applications

Her¹,

Venier-Julienne²,

Roger³

2018

Med Aromat Plants

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“…Liposome dispersions in water, similar to those produced in Gómez-Mascaraque, Casagrande Sipoli, et al (2017), were also produced for comparison purposes, by replacing the acetic acid 20% (v/v) with MilliQ water.…”

Section: Liposomes Productionmentioning

confidence: 99%

“…The lipids' 211 spectrum was obtained without further processing in ATR mode. Each recorded spectrum 212 was determined from an average of 16 scans at 4 cm -1 resolution (Gómez-Mascaraque, Casagrande Sipoli, et al, 2017).…”

Section: Fourier Transform Infrared (Ft-ir) Analysismentioning

confidence: 99%

Electrospun curcumin-loaded protein nanofiber mats as active/bioactive coatings for food packaging applications

et al. 2019

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In this study, curcumin was encapsulated within electrospun protein (i.e. gelatin and zein) 15 fibers to generate bioactive coatings for food packaging. Additionally, a green tea extract (GTE) was also incorporated within the formulations to evaluate its impact on the stability, protective ability, and release properties of the curcumin-loaded fibers. Due to the poor solubility of curcumin in aqueous media, a strategy based on its incorporation through liposomes was developed, allowing to successfully incorporating curcumin into gelatin fibers. Very high encapsulation efficiencies were attained for both zein and gelatin, with the former showing an enhanced protection effect and a more limited and slower release of the curcumin in hydrophobic food simulants. The addition of GTE resulted in strong interactions being established with the proteins and, in the particular case of gelatin, it improved the protective effect and slowed down the curcumin release from the fibers, although it did not prevent their collapse in water. The results showed that while the developed gelatin coatings showed a promising release behavior in contact with fatty food simulants, zein-based coatings would be more adequate for packaging of high water content food products.

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“…The proposed approach thus proved to be a promising alternative to produce powder-like functional ingredients [33].…”

Section: Stabilitymentioning

confidence: 98%

“…Microencapsulation of curcumin within hybrid structures, consisting of curcumin‐loaded liposomes within a protein matrix, significantly increased its bioaccessibility (∼1.seven‐fold) compared to the free compound, and could successfully stabilize it against degradation in PBS (pH = 7.4). The proposed approach thus proved to be a promising alternative to produce powder‐like functional ingredients .…”

Section: Physico‐chemical Properties Of Curcuminmentioning

confidence: 99%

Curcumin in tissue engineering: A traditional remedy for modern medicine

et al. 2018

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Curcumin is the principal polyphenolic compound present in turmeric with broad applications in tissue engineering and regenerative medicine. It has some important inherent properties with the potential to facilitate tissue healing, including anti‐inflammatory, anti‐oxidant, and antibacterial activities. Therefore, curcumin has been used for the treatment of various damaged tissues, especially wound injuries. There are different forms of curcumin, among which nano‐formulations are of a great importance in regenerative medicine. It is also important to design sophisticated delivery systems for controlled/localized delivery of curcumin to the target tissues and organs. Although there are many reports on the advantages of this compound, further research is required to fully explore its clinical usage. The review describes the physicochemical and biological properties of curcumin and the current state of the evidence on its applications in tissue engineering. © 2018 BioFactors, 45(2):135–151, 2019

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Microencapsulation structures based on protein-coated liposomes obtained through electrospraying for the stabilization and improved bioaccessibility of curcumin

Cited by 106 publications

References 42 publications

Improvement of Curcumin Bioavailability for Medical Applications

Improvement of Curcumin Bioavailability for Medical Applications

Electrospun curcumin-loaded protein nanofiber mats as active/bioactive coatings for food packaging applications

Curcumin in tissue engineering: A traditional remedy for modern medicine

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