Microencapsulation of zataria essential oil in agar, alginate and carrageenan

Kavoosi, Gholamreza; Derakhshan, Maryam; Salehi, Mohsen; Rahmati, Ladan

doi:10.1016/j.ifset.2017.12.010

Cited by 48 publications

(24 citation statements)

References 38 publications

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“…The residual mass was 37.19% of the initial mass. Similar thermal events regarding the thermal analysis of sodium alginate have been previously reported [20]. ALG/OTL-s, similar to ALG-s, also presented the same thermal events, represented by dehydration (25 to 200°C, with 11.84% of mass loss), decomposition (200 and 500°C, it was noticed a loss of mass of 27.60%), and degradation (between 500 and 800°C, with loss of mass of 13.49%).…”

Section: Resultssupporting

confidence: 82%

“…The otoliths presented thermal stability in the range of 25°to 500°C without changes in their physical state, in agreement with the data observed in TG. ALG-s presented an endothermic peak (Tpeak = 89.2°C) characteristic of dehydration of the alginate polymer [20]. An exothermic peak was observed between 200 and 270°C (Tpeak = 245°C), likely related to the oxidative degradation of the glycosidic ring in the alginate structure [22].…”

Section: Resultsmentioning

confidence: 99%

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Otoliths-composed gelatin/sodium alginate scaffolds for bone regeneration

Valido

Júnior

Andrade

et al. 2020

Drug Deliv. and Transl. Res.

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Evidence that otoliths, mineral-rich limestone concrescences present in the inner ear of bone fishes, can accelerate bone formation in vivo has been previously reported. The goal of this work was the development, characterization, and evaluation of the cytocompatibility of otoliths-incorporated sodium alginate and gelatin scaffolds. Cynoscion acoupa-derived otoliths were characterized by X-ray fluorescence spectrometry (FRX), particle size, free lime, and weight loss by calcination. Furthermore, otoliths were incorporated into sodium alginate (ALG/OTL-s) or gelatin (GEL/OTL-s) scaffolds, previously developed by freeze-drying. Then, the scaffolds were characterized by thermogravimetric analysis (TGA/DTG), differential scanning calorimetry (DSC), infrared spectroscopy with Fourier transform (FTIR), swelling tests, and scanning electron microscopy (SEM). Cytotoxicity assays were run against J774.G8 macrophages and MC3T3-E1 osteoblasts. Data obtained from TGA/DTG, DSC, and FTIR analyses confirmed the interaction between otoliths and the polymeric scaffolds. SEM showed the homogeneous porous 3D structure rich in otolith micro-fragments in both scaffolds. Swelling of the GEL/OTL-s (63.54 ± 3.0%) was greater than of ALG/ OTL-s (13.36 ± 9.9%) (p < 0.001). The viability of J774.G8 macrophages treated with both scaffolds was statistically similar to the group treated with DMEM only (p > 0.05) and significantly higher than that treated with Triton-X (p < 0.01) at 72 h. Both scaffolds showed approximately 100% growth of MC3T3-E1 osteoblasts by 24 h, similarly to control (p > 0.05). However, by 48 h, only ALG/OTL-s showed growth similar to control (p > 0.05), whereas GEL/OTL showed a significantly lower growth index (p < 0.05). In conclusion, the physicochemical profiles suggest proper interaction between the otoliths and the two developed polymeric 3D scaffolds. Moreover, both materials showed cytocompatibility with J774.G8 macrophages but the growth of MC3T3-E1 osteoblasts was higher when exposed to ALG/OTL-s. These data suggest that sodium alginate/otoliths scaffolds are potential biomaterials to be used in bone regeneration applications.

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Section: Resultssupporting

confidence: 82%

Section: Resultsmentioning

confidence: 99%

Otoliths-composed gelatin/sodium alginate scaffolds for bone regeneration

Valido

Júnior

Andrade

et al. 2020

Drug Deliv. and Transl. Res.

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“…This process is involved in the development of several common diseases, which include atherosclerosis and neurodegenerative disorders such as the Alzheimer's disease [10,11]. The antioxidant activity of phenolic compounds depends on the chemical structure, in particular, in the electron delocalization on the aromatic ring [12,13].…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Encapsulation of bis-eugenol in a Mesoporous Solid Material: Enhancement of the Antioxidant Activity of a Natural Compound from Clove Oil

Guntero

Ferretti

Mancini

et al. 2018

CSIJ

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In the present work, microwave extraction conditions to recover high eugenol content in the crude extract from clove were investigated. The effect of factors like temperature, stirring, time, liquid: Solid ratio and solutions of solvent were evaluated with Taguchi's method. The eugenol content was determined by gas chromatography. From the isolated eugenol, the bis-phenol was synthesized by the dimerization of eugenol. The encapsulation of bis-eugenol on the mesoporous silica was carried out by a microwave assisted process. Previously, mesoporous silica SBA-15 was prepared by hydrothermal synthesis using Pluronic P123 triblock copolymer as a surfactant. The bis-eugenol

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“…The encapsulation of bioactive agents may enhance their solubility, stability, efficiency, and bioavailability as well as control their release (Parris et al, 2005;Ephrem et al, 2018). Alginate microbeads have been used for the encapsulation of both low molecular and macromolecular weight agents (Ephrem et al, 2018;Kavoosi et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

GC/MS identification and applications of bioactive seaweed extracts from Mediterranean coast of Egypt

Hassan

Shobier

2018

Egypt. J. of Aquatic Biolo. and Fish.

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The antibacterial activity of different seaweed species against five fish pathogens (A. hydrophila, V. parahaemolyticus, V. alginolyticus, V. damsela and Vibrio sp.) has been evaluated. The ethanolic extract of C. sinuosa (CSE1) and dichloromethane extract of C. officinalis (COM) exhibited the highest antibacterial activity with activity index (AI) = 1.4 ±0.74 and 1.2 ±0.71, respectively. When the extracts were encapsulated into calcium alginate beads their antibacterial activity against the most susceptible bacterial pathogens showed that the significant growth inhibition was against V. parahaemolyticus after 5 min post addition of the beads recording 1.4 and 2 fold decrease in the growth, respectively. Recycling of the (CA/COM) beads was carried out for 7 successive cycles with success in elimination of V. parahaemolyticus. The potential applications of encapsulated extracts for elimination of microbial load in fish rearing water and antifouling activity were proved in the current investigation. The chemical composition of the bioactive extracts (CSE1) and (COM) was determined using GC/MS analysis which revealed the presence of several constituents that have been reported to exhibit antimicrobial activity. Additionally, the dichloromethane extract (COM) produced six major components including n-nonadecane, 1,2,3propanetricarboxylic acid, 2-(acetyloxy)-, tributyl ester, 2-methylhexadecan-1-ol, 1-docosene, 1-eicosanol and chloroacetic acid, octadecyl ester. However, the ethanolic extract (CSE1) was characterized by the presence of fatty acids, fatty acids ethyl esters and aromatic hydrocarbon where the most abundant compound was n-tridecanoic acid ethyl ester.

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Microencapsulation of zataria essential oil in agar, alginate and carrageenan

Cited by 48 publications

References 38 publications

Otoliths-composed gelatin/sodium alginate scaffolds for bone regeneration

Otoliths-composed gelatin/sodium alginate scaffolds for bone regeneration

Synthesis and Encapsulation of bis-eugenol in a Mesoporous Solid Material: Enhancement of the Antioxidant Activity of a Natural Compound from Clove Oil

GC/MS identification and applications of bioactive seaweed extracts from Mediterranean coast of Egypt

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