Microencapsulation of Fish Oil Using Hydroxypropyl Methylcellulose As a Carrier Material by Spray Drying

Abstract

Spray drying is an important method in the food industry for the production of encapsulated oil to improve the handling and flow properties of the powder. In this study, the effect of mixture of polymers on the encapsulation of fish oil by spray drying was investigated. Fish oil powder were produced using different ratios of mixtures of hydroxypropyl methylcellulose (HPMC) 15 cps and HPMC 5 cps. Scanning electron microscopy and the amount of extracted oil from the surface revealed that the formulation containing high concentration of polymer mixture provided the highest protective and prolonged effect on the covering of fish oil. The particle sizes of less than 60 μm were obtained for all the formulations. The powder density was very suitable, which improves the flowability of the powder. Microencapsulation efficiency (69.16-74.75%) and surface morphology of encapsulated oil showed that the stability was increased and hence increased its acceptability as alternative primary polymers. PRACTICAL APPLICATIONSA relatively inexpensive and food-grade particles of encapsulated fish oil could be obtained, which are free from any organic solvents. Moreover, this process, parameters and technique could be facilitated in the food, pharmaceutical and nutraceutical industries.

Dataset on applying HPMC polymer to improve encapsulation efficiency and stability of the fish oil: In vitro evaluation

“… Series Formulations HPMC 5 cps (g) HPMC 15 cps (g) PEG 6000 (g) Fish oil (g) Distilled Water (g) Solid content (wt.%) Ref. [1] [25] 1 AF1 – 10 0.5 10 179.5 10.25 AF2 – 7.5 0.5 10 182 9.0 AF3 – 5 0.5 10 184.5 7.75 AF4 – 2.5 0.5 10 187 6.5 2 BF1 10 – 0.5 10 179.5 10.25 BF2 7.5 – 0.5 10 182 9.0 BF3 5 – 0.5 10 184.5 7.75 BF4 2.5 – 0.5 10 187 6.5 …”

“…As shown in Table 3 , similar to Karim et al., [1] a moisture analyser (A&D MS-70, Japan) was used to determine the moisture content of the powder produced via the spray dried approach.…”

“…The procedures highlighted in studies like Karim et al., [1] were slightly modified to determine the total oil content.…”

“…The procedures presented in Karim et al., [1] , shown in Table 4 , was adopted the determine the sample's flowability and cohesiveness ( Table 4 ).…”

Microencapsulation of oregano (Origanum vulgare L.), rosemary (Rosmarinus officinalis L.) and sage (Salvia officinalis L.) essential oils in β-lactoglobulin

“…The encapsulation efficiency of essential oils was determined by direct solvent extraction method, using n-hexane as the solvent [36][37][38][39][40]. For each replicate, 1 g of freeze-dried powder was weighed into a centrifugation tube, which was then filled with 10 mL of nhexane.…”