Microdroplet based disposable sensor patch for detection of α-amylase in human blood serum

Disposable Electrochemical Sensor Using Graphene Oxide–Chitosan Modified Carbon-Based Electrodes for the Detection of Tyrosine

“…Due to ease of fabrication and the versatility of this approach, the use of alternative substrates, such as textiles or cloth, could also be explored for additional state of the art wearable technologies. Furthermore, given the simplicity, disability, and flexibility of the GO-CS-SPCS, integration with readout-electronics on a flexible printed circuit board (PCB) will be explored, using an approach similar to that outlined in our previous works [5], for the development of an accurate and affordable biomedical device that can be used for the real-time detection and easy prognosis of abnormal Tyr levels.…”

“…Point of care testing (POCT) of nutrients and metabolites present in the human body, and their concentrations in biofluids, forms an essential basis for health or clinical risk assessments, fast disease diagnosis and prognosis, and for the monitoring of therapeutic outcomes and the status of health conditions [4,5]. For example, tyrosine (Tyr) is a conditionally essential amino acid that serves as a building block for several vital nutritional proteins [8,9].…”

“…GO and CS were chosen for the sensitive film due to their natural abundance, excellent electrochemical sensing properties, good chemical stability, flexibility, and excellent film-forming capability. Furthermore, the affordable, biocompatible, eco-friendly, and biodegradable nature of this nanocomposite, as highlighted in our previous work, make GO and CS ideal candidates for affordable, disposable devices suitable for wearable POCT devices [5,22,46,47]. For the electrochemical detection of Tyr, an Ag/AgCl (3.0MNaCl solution) reference electrode and a Pt wire counter electrode were used, in addition to the GO-CS-SPCE.…”

High-performance printed electronics based on inorganic semiconducting nano to chip scale structures

“…Bringing multi-functionality into eSkin like devices or other wearables is important for efficient miniaturization and monitoring of different input parameters using single device [ 14 , 43 , 170 , 219 ]. The heterogeneously integrated NWs with distinct functionality will represent the future technology, where cost-competitive, scalable strategies allow integration of diverse materials with complementary performance [ 25 , 43 , 220 – 222 ].…”

“…There is growing interest in developing large-area flexible electronics for applications across numerous sectors, including wearables, robotics, consumer electronics, and healthcare [1][2][3][4][5][6]. Flexible electronics has several advantages such as conformability to different shapes, which make it indispensable for above application areas where electronic devices are needed on unconventional substrates to either conform to curvy surfaces or to degrade naturally [7][8][9][10][11][12][13][14][15][16][17][18][19][20]. Accordingly, significant research efforts are being made to develop electronic devices and systems with flexible form factors and novel manufacturing technologies [9,11,[21][22][23][24][25][26][27][28][29][30].…”