Microcantilever based Biosensor for Disease Detection Applications

Gopinath, P.; Anitha, V. R.; Mastani, S. Aruna

doi:10.12720/jomb.4.4.307-311

“…PG Gopinath et. al have proposed MEMS based low cost portable devices useful to detect various parameters like sensitivity, potential ability etc [11]. Shyamal patel et.al given review on different wearable sensor systems used in rehabilitation of the patients suffering from the neuro degenerative diseases [12].…”

Section: Literaturementioning

confidence: 99%

Design and analysis of proof mass based micro sensor for early detection of Parkinson’s disease

Prasad¹,

Shameem²,

Srinivasulu³

et al. 2017

IJET

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Micro Electro Mechanical System (MEMS) is the promising technology in bio-medical engineering which reduces the cost, sensitivity and accuracy of the devices. A Novel structure is proposed using MEMS technology in this paper. The structure comprises of a proof mass which is movable and four arms or limbs with a torus of 90 0 revolution angle. The four edges of the torus are fixed. A fixed plate is kept on the top of the proof mass to measure the capacitance and output voltage of the proposed MEMS sensor. The sensor is designed for a value of 0.4g to 0.8g. The simulated values are correlated with the theoretical values. The proposed design accurately measures tremor frequency which is in the range of 4Hz to 7Hz. The proof mass in the structure moves up and down when the device is attached to finger tip of the patient because the resting tremor or pill rolling tremor is the preliminary and basic detection symptom of Parkinson's disease. When the structure is connected to fingertip, variation in Eigen Frequency, output voltage and capacitance is measured. An amplifier is designed with a gain of 103dB and verified with the voltage so obtained from the output of the proposed sensor is 100 milli volts. There is a variation of 5% change in capacitance from theoretical to simulated values. Similarly, 8% variation in voltage. The displacement sensitivity is increased by 10%. The design is simulated using FEM tool COMSOL Multiphysics.

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“…989 motion of individual analyte molecules subjected to many challenging situations apart from using the continuity equation formulation [16].…”

Section: A Thorough Insight To Techniques For Performance Evaluation mentioning

confidence: 99%

A Thorough Insight to Techniques for Performance Evaluation in Biological Sensors

Meti¹,

Sangam²

2016

IJECE

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The biological sensor has played a significant and contributory role in the area of medical science and healthcare industry. Owing to critical healthcare usage, it is essential that such type of sensors should be highly robust, sustainable under the adverse condition and highly fault tolerant against any forms of possible system failure in future. A massive amount of research work has been done in the area of the sensor network. However, works done in biological sensors are quite less in number. Hence, this manuscript highlights all the significant research work towards the line of discussion for evaluating the effective in the techniques for performance evaluation of biological sensor. The study finally explores the problems and discusses it under research gap. Finally, the manuscript gives highlights of the future direction of the work to solve the research gap explored from the proposed review of the existing system.

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“…It is observed under the microscope that thermal fluctuation of a particle leads to follow the characteristics of typical random walk processes, as an example, it can be said that Brownian motion is the effect of subsequent diffusive spreading phenomenon or occurrence in a microscopic system. 989 motion of individual analyte molecules subjected to many challenging situations apart from using the continuity equation formulation [16].…”

Section: The Problemmentioning

confidence: 99%

A Thorough Insight to Techniques for Performance Evaluation in Biological Sensors

Meti

¹

,

Sangam

²

2016

IJECE

2

0

View full text Add to dashboard Cite

The biological sensor has played a significant and contributory role in the area of medical science and healthcare industry. Owing to critical healthcare usage, it is essential that such type of sensors should be highly robust, sustainable under the adverse condition and highly fault tolerant against any forms of possible system failure in future. A massive amount of research work has been done in the area of the sensor network. However, works done in biological sensors are quite less in number. Hence, this manuscript highlights all the significant research work towards the line of discussion for evaluating the effective in the techniques for performance evaluation of biological sensor. The study finally explores the problems and discusses it under research gap. Finally, the manuscript gives highlights of the future direction of the work to solve the research gap explored from the proposed review of the existing system.

show abstract

Microcantilever based Biosensor for Disease Detection Applications

Cited by 34 publications

References 21 publications

Design and analysis of proof mass based micro sensor for early detection of Parkinson’s disease

Design and analysis of proof mass based micro sensor for early detection of Parkinson’s disease

A Thorough Insight to Techniques for Performance Evaluation in Biological Sensors

A Thorough Insight to Techniques for Performance Evaluation in Biological Sensors

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