Microbiota intestinal: sus repercusiones clínicas en el cuerpo humano

Gigliotti, Norberto

doi:10.5546/aap.2013.523

Cited by 3 publications

(2 citation statements)

References 45 publications

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“…These variations can cause the loss of homeostasis between the intestinal microbiota and its surroundings, this is called dysbiosis, which is defined as the alteration in the composition and function of the microbiota. This condition has the ability to affect the permeability of the intestinal barrier, which causes inflammatory cascades, impaired mucosal integrity, among other harmful events at the intestinal level ( Robles-Alonso & Guarner, 2013 ; Icaza-Chávez, 2013 ; Giglio, Burgos & Cavagnari, 2013 ; Devaraj, Hemarajata & Versalovic, 2013 ). In addition to this, several studies have described that alteration in the intestinal microbiota increases the risk of susceptibility to colonization with bacterial pathogens ( Nelson et al., 2012 ).…”

Section: Introductionmentioning

confidence: 99%

Gut microbiota in hospitalized children with acute infective gastroenteritis caused by virus or bacteria in a regional Peruvian hospital

Taco-Masias

Fernandez-Aristi

Cornejo-Tapia

et al. 2020

PeerJ

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Background Acute infective gastroenteritis (AIG) is a leading cause of mortality in children worldwide. In Peru, more than 40% of cases of AIG occurring in children under 5 years old. The disruption of the gut microbiota can increase risk for several health complications especially in patients with gastric infections caused by viruses or bacteria. Objective The main objective of this study was to describe the prevalence of 13 representative bacteria from the gut microbiota (GM) in stools samples from children under 5 years of age with acute infective gastroenteritis. Results The most commonly isolated bacteria from the GM were Firmicutes (63.2% 74/117) Bacteriodetes (62.4%; 73/117), Lactobacillus (59.8%; 70/117), Prevotella (57.2%; 67/117), Proteobacterium (53.8%; 63/117), regardless of the etiological agent responsible for the AIG. Interestingly, despite the high prevalence of Firmicutes, Bacteroidetes, Lactobacillus and Prevotella across all samples, a visible reduction of these agents was observed especially among patients with a single bacterial infection or even bacteria–bacteria coinfections when compared to viral etiologies. Patients with exclusive or mixed breastfeeding registered the highest amount of gut microbiota bacteria, in contrast to infants who received formula or were not breastfed.

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Section: Introductionmentioning

confidence: 99%

Gut microbiota in hospitalized children with acute infective gastroenteritis caused by virus or bacteria in a regional Peruvian hospital

Taco-Masias

Fernandez-Aristi

Cornejo-Tapia

et al. 2020

PeerJ

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“…Alterations in the composition and function of the microbiota, denominated dysbiosis, can affect intestinal permeability and alter mucosa integrity. This process can produce an increase of monosaccharides absorption, synthesis of fatty acids on the liver and alter hormonal production in entero-endocrine cells [ 9 , 10 , 12 , 19 ]. Recent studies have shown variations in the population of bacteria residing in the gut among healthy individuals and patients with T2DM, which have implications on pathogenesis and treatment of the disease [ 20 , 21 ].…”

Section: Introductionmentioning

confidence: 99%

Characterization of the gut microbiota in diabetes mellitus II patients with adequate and inadequate metabolic control

et al. 2021

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Objective The objective of this study was to characterize the composition of the gut microbiota in type 2 Diabetes Mellitus (T2DM) patients with adequate and inadequate metabolic control, and its relationship with fiber consumption. Results A total of 26 patients with type 2 diabetes mellitus (T2DM) were enrolled, of which 7 (26.9%) cases had adequate metabolic control (HbA1c < 7%) and 19 (73.1%) inadequate metabolic control (HbA1c ≥ 7%). It was observed that among patients with controlled T2DM, 2 (28.6%) cases presented good intake of fiber and 5 (71.4%) cases a regular intake. In contrast, in patients with uncontrolled T2DM, 13 (68.4%) patients reported a regular intake and 6 (31.6%) a poor intake. In relation to the identification of the gut microbiota, both groups presented a similar characterization. There were differences in the population of bacteria identified in both groups, however, the results were not statistically significant. The most frequently identified bacteria in controlled and uncontrolled T2DM patients were Prevotella (71.4% vs 52.6%), followed by Firmicutes (71.4% vs 42.1%), Proteobacteria (71.4% vs 36.8%) and Bacteroidetes (57.1% vs 37.8%). On the other hand, Fusobacterium, Actinobacteria were not identified in either of the two groups of study.

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Environmental and Social Determinants Related to Candidiasis

del Carmen Morales-Ramírez,

Avila-Sosa,

Soledad Cid-Pérez

et al. 2024

Candida Albicans - Epidemiology and Treatment [Working Title]

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Environmental, social, and economic factors are decisive for susceptibility to infectious diseases caused by opportunistic pathogens, such as Candida. Their incidence has increased significantly in recent years, mainly due to a greater number of immunocompromised people, the social and economic environment in which they develop and the current environmental crisis, climate change, which exacerbates health inequalities. Therefore, a literature review was conducted on the main social and environmental determinants of health and virulence factors as determinants of Candida spp. infection. Several studies provide valuable insights into the main predisposing determinants of Candida colonization and infection in relation to the health status of people and the virulence factors of the aetiological pathogen itself. Although there are some studies on the prevalence of Candida in different social classes, there are still few criteria to derive or claim an objective opinion on the social conditions under which this opportunistic pathogen occurs. Therefore, an overall picture that takes into account not only the intrinsic factors of the individual (human biology, health status, etc.) but also the social determinants of health, which may be related to differences in colonization and infection by different Candida species, is still lacking.

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Microbiota intestinal: sus repercusiones clínicas en el cuerpo humano

Cited by 3 publications

References 45 publications

Gut microbiota in hospitalized children with acute infective gastroenteritis caused by virus or bacteria in a regional Peruvian hospital

Gut microbiota in hospitalized children with acute infective gastroenteritis caused by virus or bacteria in a regional Peruvian hospital

Characterization of the gut microbiota in diabetes mellitus II patients with adequate and inadequate metabolic control

Environmental and Social Determinants Related to Candidiasis

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