Microbiota Influences Host Exercise Capacity Via Modulation of Skeletal Muscle Glucose Metabolism in Mice

Astaxanthin slows down skeletal muscle atrophy in H22 tumor-bearing mice during sorafenib treatment by modulating the gut microbiota

“…45,46 Mitochondria are the main site of oxidative phosphorylation in skeletal muscle, and functional impairment of mitochondria is often found in skeletal muscle atrophy due to cancer cachexia. [47][48][49] Repairing mitochondrial dysfunction can help enhance the efficiency of energy production and slow down glycolysis in skeletal muscle. 2,50,51 The skeletal muscle of GF mice exhibited…”