Microbiota fúngica no ar em unidades de terapia intensiva e centros cirúrgicos

Andrade, Daniela Furtado Rodrigues de; Silva, Helen Maria Gomes da; Carvalho, Valécia; Sousa, Marcos André Siqueira de; Nunes, Maria do Rosário Conceição Moura; Freitas, Daniela Reis Joaquim de

doi:10.26694/repis.v1i1.3210

Cited by 2 publications

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“…Finally, there are the filamentous fungi that are highly lethal, among which is the genus Aspergillus, known to include opportunistic species that are frequently encountered in intensive care units and surgical centres, responsible for the cause of endocarditis and pulmonary infections [46]. Based on our results, HEBe may be a potential candidate in the treatment of fungal illnesses, although further pharmacological and phytochemical studies for the clarification of its mechanism of action and identification of the compounds responsible for this effect.…”

Section: Antifungal Activitymentioning

confidence: 99%

Antimicrobial and Antioxidant Activities of Selected Plants Used by Populations From Juruena Valley, Legal Amazon, Brazil

Silva

Arunachalam

Miyajima

et al. 2017

Int J Pharm Pharm Sci

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Objective: The purpose of this study was to evaluate selected Brazilian plants from Juruena valley region of Mato Grosso, for their in vitro antimicrobial and antioxidant activities. Methods:The powder obtained from different parts of the twenty-six (26) plants were macerated in hydroethanolic solution to obtain the extracts. The hydroethanolic extracts were tested for their in vitro antimicrobial activity by determining the MIC using broth microdilution. The 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical, ferric reducing antioxidant power (FRAP) and nitric oxide (NO) methods were used for the determination of antioxidant activities. Correlation between classes of secondary metabolites and antioxidant activity was assessed.Results: Phanera glabra extract (HEPg) showed broad antibacterial spectrum, presenting the best activity against Klebsiella pneumoniae. Hevea microphylla extract (HEHm) presented a narrow spectrum of antibacterial activity with strong effect against Shigella flexneri. The only plant with broad spectrum antifungal activity was Bertholletia excelsa (HEBe), with moderate activity against strains of Aspergillus and Candida. The following extracts were prominent regarding their activities in the DPPH and FRAP assays-HEBe, Cariniana rubra (HECr) and in the FRAP assay alone, Cedrela odorata (HECo) and HEPg. None of the extracts was active in the NO assay. A significant association was observed between DPPH activity and the total phenolic contents. Conclusion:Our results justified the use of some of the investigated plants in the Brazilian ethnomedicine. The antibacterial activities of these plants are bacteriostatic in nature. These findings support that a number of investigated plants could be a valuable source of new antioxidant and antimicrobial compounds that can potentially deliver novel mechanisms of actions. However, further studies are required.

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Section: Antifungal Activitymentioning

confidence: 99%

Antimicrobial and Antioxidant Activities of Selected Plants Used by Populations From Juruena Valley, Legal Amazon, Brazil

Silva

Arunachalam

Miyajima

et al. 2017

Int J Pharm Pharm Sci

View full text Add to dashboard Cite

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Analysis of fungal microbiota of ambient air in an intensive care unit in Rio Branco, Acre, Western Amazon, Brazil

Ribeiro,

Prado

et al. 2023

Braz. J. Biol.

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Fungi exhibit three adverse effects on human health: inflammatory, allergic and toxic effects, these implications affect mainly immunodepressed patients. The objective of this work was to analyze the fungal microbiota of the ambient air of an Intensive Care Unit. Three collections were carried out in an Intensive Care Unit in the city of Rio Branco, Acre, Western Amazon, Brazil from March to May 2017. 126 Petri dishes were exposed with the culture medium Agar Sabouraud with chloramphenicol and Agar Mycosel, considering the distribution of the 21 air conditioners, split residential model. The plates were incubated for seven days at room temperature and the growth of Colony Forming Units was observed. Colony counting and isolation for the morphological characterization of the granted fungi was performed. After quantification, the concentration of fungi per cubic meters of air (CFU.m-3) was settled. The third collection had a larger number of colony forming units with 48.6%. In the total of the analyzed samples, filamentous fungi (85.5%) and yeasts (14.5%) were isolated. Thirteen genera of fungi were identified, with the most frequent filaments being Cladosporium spp. 33.0%, Aspergillus spp. 30.4% and Penicillium spp. 19.6%, and yeasts Candida spp. 52.6%, Trichosporon spp. 36.9%. The colony-forming unit per cubic meter (CFU.m-3) did not shown any difference between the Cores in the same collection period, however in the 1st and 3rd collection, Core 1 had the highest average. The fungal microbiota of this Unit presented thirteen different genera potentially pathogenic, revealing the need for monitoring microorganisms and prevention actions.

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Microbiota fúngica no ar em unidades de terapia intensiva e centros cirúrgicos

Cited by 2 publications

References 0 publications

Antimicrobial and Antioxidant Activities of Selected Plants Used by Populations From Juruena Valley, Legal Amazon, Brazil

Antimicrobial and Antioxidant Activities of Selected Plants Used by Populations From Juruena Valley, Legal Amazon, Brazil

Analysis of fungal microbiota of ambient air in an intensive care unit in Rio Branco, Acre, Western Amazon, Brazil

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