Microbiota from human infants consuming secretors or non-secretors mothers’ milk impacts the gut and immune system in mice
Manoj Gurung,
Brent Thomas Schlegel,
Dhivyaa Rajasundaram
et al.
Abstract:Maternal secretor status is one of the determinants of human milk oligosaccharides (HMOs) composition, which, in turn, influences the gut microbiota composition of infants. To understand if this change in gut microbiota impacts immune cell composition, intestinal morphology, and gene expression, 21-day-old germ-free C57BL/6 mice were transplanted with fecal microbiota from infants whose mothers were either secretors (SMM) or non-secretors (NSM) or from infants consuming dairy-based formula (MFM). For each grou… Show more
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