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2022
DOI: 10.3390/jcm11237074
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Microbiome of Acute Otitis Externa

Abstract: Background: Ear canal skin is directly attached to bone or cartilage, and is also connected to the eardrum. Acute otitis externa is cellulitis of the ear canal skin and subdermal tissue associated with acute inflammation and variable edema. We characterized the microbiome of the normal ear canal and ear canal with otitis externa. Methods: In total, 28 samples (14 each from the ear canal skin of patients with acute otitis externa and normal healthy controls) were collected using swabs. DNA extraction and bacter… Show more

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Cited by 2 publications
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“…Epithelial homeostasis and tissue health are maintained by skin commensals. Bacterial overproliferation can trigger skin inflammation and diseases [ 9 ]. As shown in Figure-2 , the most common cause of otitis externa was bacterial infection, whereas the most common bacterial genera found in the ear canal were Staphylococcus , Pseudomonas , and Proteus .…”
Section: Discussionmentioning
confidence: 99%
“…Epithelial homeostasis and tissue health are maintained by skin commensals. Bacterial overproliferation can trigger skin inflammation and diseases [ 9 ]. As shown in Figure-2 , the most common cause of otitis externa was bacterial infection, whereas the most common bacterial genera found in the ear canal were Staphylococcus , Pseudomonas , and Proteus .…”
Section: Discussionmentioning
confidence: 99%
“…The most common cause of acute otitis externa is a bacterial infection caused by Pseudomonas aeruginosa (20-60% prevalence) and Staphylococcus aureus (10-70% prevalence), 2 of 10 occurring as a polymicrobial infection [5]. Rarely, it may result from a fungal infection caused by Candida albicans or Aspergillus sp [6].…”
Section: Introductionmentioning
confidence: 99%