Microbiome-derived metabolite effects on intestinal barrier integrity and immune cell response to infection
Lauren Adams,
Xiang Li,
Richard Burchmore
et al.
Abstract:The gut microbiota exerts a significant influence on human health and disease. While compositional changes in the gut microbiota in specific diseases can easily be determined, we lack a detailed mechanistic understanding of how these changes exert effects at the cellular level. However, the putative local and systemic effects on human physiology that are attributed to the gut microbiota are clearly being mediated through molecular communication. Here we determined the effects of a number of gut microbiome-deri… Show more
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