Microbiology. Louis P. Gebhardt and Dean A. Anderson. Mosby, St. Louis, ed. 2, 1959. 476 pp. Illus. S5.75

Tetralogy of Fallot in a Calf: Clinical, Ultrasonographic, Laboratory and Postmortem Findings

“…The defect is caused by abnormal development of the conal septum in the embryonic heart, which leads to narrowing of the right ventricular infundibulum (pulmonic stenosis; PS), an inability of the conal septum to participate in closure of the interventricular foramen (ventricular septal defect; VSD) and overriding of the aorta. Right ventricular hypertrophy (RVH) develops as a result of PS [15]. An accurate diagnosis of the disease in the calf is valuable for making a decision regarding the animal's prognosis.…”

“…The RVH usually follows secondary to the PS, and the degree of aortic malpositioning is variable and of limited hemodynamic importance. The pathophysiology of TOF and related lesions depends on (1) the size of the VSD, (2) the severity of the PS and (3) the systemic vascular resistance [15].…”

Immunohistochemical Localization of Secretory Immuno-globulins in the Main Excretory Duct of the Human Submandibular Gland.

“…Detection of IgM and IgG in saliva may indicate a compensatory protection of the mucosa against infections. In fact, in patients with selective IgAdeficiency, IgM occurred in a pattern similar to that normally seen for IgA (KORSRUD and BRANDTZAEG, 1980;SMITH, 1992).…”

Failure of Pyridoxine to Change the Transfusion Requirement of Patients with Thalassemia Major

“…Patients with thalassemia major require numerous transfusions, ultimately resulting in a secondary hemochromatosis characterized by enlargement of their livers and a tanned, bronze coloration of their skin with a marked degree of fine, dark, stippled-like freckles. Postmortem examination of these patients have demonstrated that these enlarged livers contain enormous quantities of iron-containing pigment distributed diffusely in a pattern similar to that of primary hemochromatosis (10). The exact defect in hemoglobin synthesis in these patients is unknown.…”