Microbiological study in clinically characterized rapidly progressive periodontal disease.

Abstract

Samples of subgingival bacteria were collected from two sites of anteriors with• †6mm deep pockets in each ten patients in a clinically characterized rapidly progressive periodontal disease.

Microbiology of periodontal disease in children and young adults

“…van Winkelhoff et al (171) demonstrated that the elimination of A. actinomycetemcomitans by hygiene phase therapy and antibiotics from ten generalized early‐onset periodontitis patients resulted in clinical improvement and that the one patient that was still A. actinomycetemcomitans –positive after treatment did not improve clinically. Conversely, Masunaga et al (97) reported that the levels of A. actinomycetemcomitans were not changed by scaling and root planing, and the reduction in pocket depth was due to the elimination of P. intermedia and P. gingivalis .…”

“…Lopez et al (90) found A. actinomycetemcomitans in 60% of generalized early‐onset periodontitis patients and 50% of affected sites. However, Vandesteen et al (174), Williams et al (182), Moore et al (104) and Lopez et al (91) did not detect A. actinomycetemcomitans in generalized early‐onset periodontitis patients, and although A. actinomycetemcomitans is present in some patients, other organisms such as P. gingivalis , P. intermedia , F. nucleatum and B. forsythus are found with greater frequency and numbers (73, 97, 118, 141). Listgarten et al (85) reported that A. actinomycetemcomitans serotype b was the most common, followed by serotype a and then serotype c.…”

“…A number of researchers have found A. actinomycetemcomitans in generalized early‐onset periodontitis patients (73, 75, 85, 90, 97, 98, 112, 116, 120, 141, 145, 171) (Table 3). The frequency and numbers of the organism are increased, with Okuda et al (120) finding that up to 20% of the subgingival microbiota consisted of A. actinomycetemcomitans .…”

“…P. gingivalis has also been implicated in generalized early‐onset periodontitis in a number of studies (3, 36, 73–75, 85, 88, 90, 91, 97, 104, 118, 141, 174) (Table 3) and is often the predominant organism in the disease (2, 73, 74, 90, 118, 174). Wilson et al (182) found that 8% to 16% of the cultivable microflora was P. gingivalis and suggested that P. gingivalis was involved in causing generalized early‐onset periodotitis.…”

“…Williams et al (182) did not detect P. gingivalis in their study of generalized early‐onset periodontitis. P. gingivalis has also been frequently isolated with P. intermedia (2, 36, 97, 174), A. actinomycetemcomitans (73, 85, 97), F. nucleatum (118) or a combination of these including Bacteroides forsythus (74, 75, 141).…”