Microbiological Profile of Diabetic Foot Infections in a Tertiary Care Hospital in Navi Mumbai

Abstract

Original Research Article Diabetic foot ulcers are most common serious consequences of diabetes. The proper management of diabetic foot infection (DFI) requires a detailed knowledge about the microbial spectrum and their antibiogram. In this study, 123 cases with DFI were studied. Pus swabs and deep tissue/ bone samples were collected. We observed 74.8% & 16.2% cases were monomicrobial and polymicrobial in nature, respectively. Pseudomonas aeruginosa (29.5%) was the most commonly isolated organism followed by Staphylococcus aureus (16.6%) and Escherichia coli (12.8%). We observed 27.27% strains of Methicillin Resistant Staphylococcus aureus (MRSA) & 100% Extended Spectrum Beta Lactamases (ESBLs) strains of enterobacteriacae. All the gram positive organisms, Staphylococcus aureus, Enterococcus faecalis and Coagulase negative Staphylococcus were sensitive to vancomycin (100%) and Linezolid (100%). Pseudomonas aeruginosa isolates were 100% sensitive to Amikacin and Tobramicin, Piperacillin-Tazobactm and Ciprofloxacin. Klebsiella pneumoniae showed high resistance to Cefepime (87.5%) and Piperacillin-Tazobactm (75%). Escherichea coli isolate showed 100% sensitivity towards Gentamicin. Acinetobacter baumanni showed 100% sensitivity for Imipenem and Meropenem.