Microbiological follow-up of Nosocomial Infections in a Single Urological Center

Vittori, Matteo; D’Addessi, Alessandro; Sasso, Francesco; Sacco, Emilio; Totaro, Angelo; Calarco, Alessandro; D’Agostino, Daniele; Palermo, Giuseppe; Bassi, Pier Francesco

doi:10.5301/ru.2012.9372

Cited by 3 publications

(5 citation statements)

References 12 publications

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“…Coli, la Klebsiella Pneumoniae et le Pseudomonas Aeroginosa. Ceci a également été retrouvé dans plusieurs séries internationales [ 7 – 9 ]. De récentes données américaines indiquent qu'E.…”

Section: Discussionunclassified

“…Cela a été illustré dans une étude prospective incluant 100 adultes suédois qui,deretour chez eux après une durée moyenne de séjour de 02 semaines, étaient colonisés par une souche E. coli productrices de BLSE dans presque le ¼ des cas 17 . Les facteurs de risque liés à la survenue d'IUN dans notre étuderejoignent ceux de la littérature, à savoir: le sexe féminin, le sondage urinaire et l'infection urinaire à répétition [ 7 , 18 ]. Dans notre série le diabète et la lithiase urinaire ne sont pas ressortis comme facteurs de risque statistiquement significatifs, ceci est expliqué du fait que le pourcentage des patients connus diabétiques ou porteurs de lithiase urinaire est presque à pied d’égalité dans les deux groupes comparés (groupes porteurs d'IUN et groupe non infecté).…”

Section: Discussionunclassified

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Profil de l’infection urinaire nosocomiale dans un service de néphrologie

Lazrak¹,

Bardai²,

Jaafour³

et al. 2014

Pan Afr Med J

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L'infection urinaire est l'infection nosocomiale la plus fréquente. Elle constitue un véritable problème de santé publique par la surmortalité et le surcoût qu'elle entraîne. L'objectif de notre étude est de déterminer l'incidence et le profil des IU nosocomiales dans un service de Néphrologie. Etude rétrospective sur dossier de tous les patients hospitalisés dans notre service durant l'année 2011, ayant bénéficié d'un examen cytobactériologique des urines. Ont été exclus, tous les patients admis avec une IU connue ou active. 325 dossiers ont été retenus. L'incidence de l'IU nosocomiale était de l'ordre de 16,9%. La durée moyenne d'hospitalisation était de 14,1±10,15 jours. 30% de nos patients ont été transférés du service des urgences. 80% des IU nosocomiales étaient compliquées. Le germe responsable était E.Coli dans 2/3 des cas dont 14,5% était à E.Coli sécrétrice de bétalactamases à spectre étendu. L’évolution après traitement était favorable chez 90,7%. En analyse multivariée, les facteurs de risque pour contracter une IU nosocomiale étaient le sexe féminin; le sondage urinaire et l'antécédent d'IU à répétition. Nos résultats rejoignent ceux de la littérature concernant les facteurs de risque liés à la survenue de l'IU nosocomiale, la fréquence des infections à entérobactéries, et l’émergence de souches résistantes. Une Surveillance microbiologique et une évaluation de la résistance aux antibiotiques constituent une ligne de défense pour faire face à l'accentuation de nouvelles souches bactériennes de plus en plus résistantes aux antibiotiques rendant les options thérapeutiques très limitées.

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Section: Discussionunclassified

Profil de l’infection urinaire nosocomiale dans un service de néphrologie

Lazrak¹,

Bardai²,

Jaafour³

et al. 2014

Pan Afr Med J

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“…25,26 The evaluation of local bacteria epidemiology and susceptibility profile is of utmost importance and should be performed in all healthcare facilities to identify the correct agent to administer. 27,28 When the risk of negative outcomes in the case of SSIs is low or minimal, despite the presence of scant data on the topic, a good choice can be represented by an aminoglycoside or a second-generation cephalosporin, as an alternative. 29,30 No pieces of advice are given in European guidelines about the type of drug to use in high-risk procedures.…”

Section: Antibiotic Selection and Administration Routementioning

confidence: 99%

“…The evaluation of local bacteria epidemiology and susceptibility profile is of utmost importance and should be performed in all healthcare facilities to identify the correct agent to administer. 27,28…”

Section: Aims and Principles Of Antibiotic Prophylaxismentioning

confidence: 99%

Antibiotic prophylaxis in urologic interventions: Who, when, where?

Marino,

Rossi,

Murri

et al. 2024

Urologia

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Background: Periprocedural prophylaxis in medicine encompasses the set of measures (physical, chemical, and pharmacological) used to reduce the risk of infection. Antibiotic prophylaxis (AP) refers to the administration of a short-term regimen of antibiotics shortly before a medical procedure to reduce the risk of infectious complications that can result from diagnostic and therapeutic interventions. The outspreading growth of multidrug-resistant bacterial species and changes in the bacterial local ecosystem have impeded the development of a unique scheme of AP in urology. Objectives: To review the literature and current guidelines regarding AP for urological diagnostic and therapeutic procedures, and to define agents, timing, and occasions when administering pharmacological prophylaxis. Secondly, according to current literature, to open new scenarios where AP can be useful or useless. Results: Major gaps in evidence still exist in this field. AP appears useful in many invasive procedures and some sub-populations at risk of infectious complications. AP is not routinely recommended for urodynamic exams, diagnostic cystoscopy, and extracorporeal shock-wave lithotripsy. The available data regarding the use of AP during the transperineal prostate biopsy are still unclear; conversely, in the case of the transrectal approach AP is mandatory. AP is still considered the gold standard for the prevention of postoperative infective complications in the case of ureteroscopy, percutaneous nephrolithotomy, endoscopic resection of bladder tumor, endoscopic resection of the prostate, and prosthetic or major surgery. Conclusion: The review highlights the complexity of determining the appropriate candidates for AP, emphasizing the importance of considering patient-specific factors such as comorbidities, immunocompetence, and the nature of the urologic intervention. The evidence suggests that a one-size-fits-all approach may not be suitable, and a tailored strategy based on the specific procedure and patient characteristics is essential.

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“…Remaining UTIs are caused by various organisms, including staphylococci, proteus organisms, Klebsiella spp., and Enterococcus faecalis. The incidence of UTIs related to S. aureus was found to be 3.5%, based on an analysis of 321 patients over a 3-year period [9]. Pathogenic bacteria have the ability to adhere to inert surfaces, such as a catheter, which leads to device-associated infections.…”

Section: Introductionmentioning

confidence: 99%

Using Atomic Force Microscopy to Measure Anti-Adhesion Effects on Uropathogenic Bacteria, Observed in Urine after Cranberry Juice Consumption

Abu-Lail¹,

Tao²,

Pinzón-Arango³

et al. 2012

JBNB

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A volunteer was given cranberry juice cocktail (CJC) or water to drink, and urine was collected at 2 and 8 hours after consumption, in order to quantitatively determine whether adhesion forces were changed for the volunteer after CJC consumption. Atomic force microscopy (AFM) was used to measure adhesion forces between bacteria and a silicon nitride tip. Forces between Escherichia coli or Staphylococcus aureus and the AFM tip were lower in the urine after the volunteer consumed CJC, compared to drinking water. A steric model was applied to the AFM data, in order to quantify how the urine changed the properties of the bacterial surfaces. There was a small decrease in the equilibrium length of surface molecules on the bacteria when in the post-CJC urine, compared to the post-water urine. However, these changes were not statistically significant. We hypothesize that post-CJC urine imparts subtle changes on the molecules of the bacterial surfaces, and that these changes lead to the reduction in adhesion with the AFM probe.

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Microbiological follow-up of Nosocomial Infections in a Single Urological Center

Cited by 3 publications

References 12 publications

Profil de l’infection urinaire nosocomiale dans un service de néphrologie

Profil de l’infection urinaire nosocomiale dans un service de néphrologie

Antibiotic prophylaxis in urologic interventions: Who, when, where?

Using Atomic Force Microscopy to Measure Anti-Adhesion Effects on Uropathogenic Bacteria, Observed in Urine after Cranberry Juice Consumption

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