Microbiological evaluation of UV disinfection effectiveness in a specialist cystic fibrosis clinic

Abstract

The aim of the study was to evaluate the impact of manual cleaning and manual cleaning followed by Ultraviolet-C disinfection on the colony forming units of bacteria retrievable from equipment and surfaces within clinic rooms following a CF outpatient encounter. While UV disinfection has proven to be effective within general healthcare settings, it has not been evaluated in a CF centre. Microbiological sampling was performed following outpatient encounters involving 11 adult patients with CF and chronic infection with P.aeruginosa, MRSA or E. coli ESBL. The results of this study suggest that manual cleaning followed by UV-C disinfection is more effective than manual cleaning alone at reducing environmental contamination within a CF clinic and that UV-C isinfection is likely to reduce the risk of fomite transmission in the CF outpatient setting.

Cystic fibrosis year in review 2019: Section 2 pulmonary disease and infections

“…An adult CF clinic found that adding Ultraviolet‐C disinfection to surface cleaning reduced the number of colony forming units (CFUs) cultured via surface swabs in spirometers, sink and tap, door or handle, and desk or chair. The CFUs were reduced to essentially zero in this small sample and required minimal time (10–20 minutes per room, per patient) 1 . Cleaning and disinfecting respiratory equipment at home is recommended but is time‐consuming.…”

“…The CFUs were reduced to essentially zero in this small sample and required minimal time (10-20 minutes per room, per patient). 1 Cleaning and disinfecting respiratory equipment at home is recommended but is time-consuming. One center assessed knowledge and attitudes toward cleaning and disinfection, finding that most people with CF had positive attitudes towards cleaning and disinfection, but only about 45% disinfected daily or after each use.…”

Hospital surface disinfection using ultraviolet germicidal irradiation technology: A review

“…UVGI studies have targeted pathogens responsible for the majority of HCAI fatalities [26], including methicillin-resistant Staphylococcus aureus (MRSA) (21 papers), vancomycin-resistant Enterococcus (VRE) (14 papers) and Clostridioides difficile (18 papers). Other pathogens of interest included Escherichia coli [36,43,44,46], Klebsiella pneumoniae [43,46,50,55] and Pseudomonas aeruginosa [36,43,50,69,44,46]. The pathogens that were specifically targeted in UVGI studies are summarised in Table 6.…”

Evidence Map and Systematic Review of Disinfection Efficacy on Environmental Surfaces in Healthcare Facilities

“…Sodium hypochlorite disinfection, which comprised any disinfection method specified as bleach or sodium hypochlorite, was identified in 19% of studies [20,44,60,61,75,89,95,97,100,104,109,. Other chlorine disinfectants were identified in 14% of studies [65,70,78,101,118,[135][136][137][138][139][140][141][142][143][144][145][146][147][148][149][150][151][152][153][154]. Other chlorines included demand-release chlorines such as sodium dichloroisocyanurate, chloramine, chlorine-dioxide, and bromochloro-dimethyl-hydantoin, as well as electrolyzed water, hypochlorous acid, and any unspecified chlorine-based disinfectant.…”