Microbiological aspects of leg ulcers

Hayes, M.

doi:10.12968/jowc.1997.6.2.98

Cited by 8 publications

(3 citation statements)

References 9 publications

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“…These isolates are common isolates found in wounds (9,25). These isolates contribute to pathology of the wound infection, for example Streptococcal invasion of wound delays healing as well as results in deterioration of wounds (27). Pseudomonas spp, Enterococci spp, and Proteus spp are responsible for extensive tissue destruction with poor blood circulation to the affected site especially diabetic foot ulcer (28).…”

Section: Resultsmentioning

confidence: 99%

Aerobic bacterial isolates from infected wounds

Esebelahie¹,

Newton-Esebelahie²,

Omoregie³

2013

Af J Clin Exp Micro

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Background: Wound infection causes great distress in terms of associated mortality and morbidity, increased length of hospital stay, profound discomfort and significant increased in healthcare cost. Infection in a wound delays healing and may cause wound break down, herniation of the wound and complete wound dehiscence.Therefore the knowledge of the causative agents of wound infection will be helpful in the control of wound infection and selection of empiric antimicrobial therapy as an infection control measure. Methods:A total of 207 wound specimens collected from patients attending the University of Benin Teaching Hospital were used for this study. All specimens were collected using sterile swabs sticks. Specimens were processed using standard microbiological methods. Results:A total of 278 bacterial isolates were obtained from 207 wound specimens processed in this study. Positive growth were observed in 185 (89.4%) of the wound cultures and no bacterial isolates were obtained in 22 (21.1%) of the cultured materials. Staphylococcus aureus (26.9%) was the most predominant isolate followed by Klebsiellapneumoniae (17.6%), Pseudomonas aeruginosa (16.9%) and Escherichia coli (12.6%). All isolates were resistant to ampicillin, amoxyillin-clavulanate and tetracycline but show variable susceptibility to other antibacterial used. Majority of the isolates produced beta lactamase. Conclusion: A high proportion of the wounds were infected.The variety of microorganisms observed in this study support the need to obtain culture specimen from infected wounds for microbiological evaluation and antibiotic susceptibility determination, so that adapted chemotherapy can be prescribed.

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Section: Resultsmentioning

confidence: 99%

Aerobic bacterial isolates from infected wounds

Esebelahie¹,

Newton-Esebelahie²,

Omoregie³

2013

Af J Clin Exp Micro

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“…This is supported by Lawrence (1993a) who recorded the percentage incidence of bacteria in 58 venous ulcers. A review of leg ulcer bacteriology concluded that although streptococcal invasion was unlikely to initiate ulceration, it resulted in ulcer deterioration or delayed healing (Hayes 1997).…”

Section: Inadequate Antibiotic Prophylaxismentioning

confidence: 99%

“…Bowler and Davies (1999) suggest that because of the variety of mixed flora in ulcers and the increase in anaerobic species in infected ulcers, aerobic-anaerobic synergism might be of greater importance than any specific pathogen in the development of wound infection. Hayes (1997) stated that little more was needed to determine the flora of leg ulcers and that the next step was to determine the interaction of the bacteria with the host. On investigating wound healing, Trengove et al (1996) found that bacterial groups in ulcers change over time, but that with the exception of skin flora, these changes were not related to changes in wound healing.…”

Section: Inadequate Antibiotic Prophylaxismentioning

confidence: 99%

A proactive approach to wound infection

Kingsley

2001

Nursing Standard

119

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The effect of bacteria on leg ulcer healing

Harker

2001

Br J Community Nurs

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It is a common belief that bacterial infection will delay the healing of leg ulcers, or lead to a deterioration in the wound bed or surrounding skin. Despite many years of research however, there is still no agreement on whether this is in fact the case. This article reviews a selection of the available literature regarding the effects of bacteria on leg ulcer healing. Attempts have been made to distinguish differing levels of bacterial presence (e.g. contamination, colonization, infection), but these terms are still loosely applied and consequently ill-defined. Furthermore, the variety of treatment and assessment methods used in the various studies hampers their comparison. The article concludes that future studies should adhere to a uniform methodology in order to provide clear evidence on which to base practice.

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Microbiological aspects of leg ulcers

Abstract: In the second part of a review of leg ulcer studies, the significance of microbial colonisation is explored and suggestions are offered for the direction of future research

Cited by 8 publications

References 9 publications

Aerobic bacterial isolates from infected wounds

Aerobic bacterial isolates from infected wounds

A proactive approach to wound infection

The effect of bacteria on leg ulcer healing

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