Microbicidal activity of TiO<sub>2</sub>nanoparticles synthesised by sol–gel method

Priyanka, K. P.; Sukirtha, Thiruvangium Henry; Balakrishna, Keshava; Varghese, Thomas

doi:10.1049/iet-nbt.2015.0038

Cited by 49 publications

(23 citation statements)

References 25 publications

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“…It induces the decomposition of bacterial outer membranes by reactive oxygen species. It may cause phospholipid peroxidation and cell death [12, 15–19].…”

Section: Resultsmentioning

confidence: 99%

“…The screening of antibiotics was done to identify the standard antibiotic activity against the pathogenic organisms such as Gram‐positive ( S. aureus and S. pyogenes ) and Gram‐negative ( E coli , K. pneumoniae and P. mirabilis ) bacterial strains using the modified Kirby–Bauer disc diffusion method [11, 12]. Antibiotics tetracycline, erythromycin, bacitracin, amoxicillin, cefexime, and ampicillin were selected for the screening.…”

Section: Methodsmentioning

confidence: 99%

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Antibacterial activity of carbon nanoparticles isolated from chimney soot

Aloysius¹,

Varghese²,

Ali³

et al. 2019

IET nanobiotechnol.

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Carbon nanoparticles (CNPs) are isolated from chimney soot and characterised by various tools such as X-ray diffraction, scanning electron microscopy, transmission electron microscopy and ultraviolet-visible spectroscopy. The X-ray diffraction studies confirm the presence of C 60 nanoparticles in the isolated sample. The thermal properties of the prepared CNPs are recorded using thermogravimetric analysis and differential thermal analysis. The analysis of the antibacterial activity of the synthesised CNPs against selected Gram-positive and Gram-negative bacterial strains is also investigated. The systematic study confirms that CNPs collected from chimney soot exhibit good antibacterial potency against Staphylococcus aureus, Streptococcus pyogenes, Klebsiella pneumoniae, and Proteus mirabilis.

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“…It induces the decomposition of bacterial outer membranes by reactive oxygen species. It may cause phospholipid peroxidation and cell death [12, 15–19].…”

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Antibacterial activity of carbon nanoparticles isolated from chimney soot

Aloysius¹,

Varghese²,

Ali³

et al. 2019

IET nanobiotechnol.

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“…Titanium oxide (TiO2) NPs have been widely used as photocatalysts among all photocatalytic compounds (Ravishankar Rai and Jamuna Bai, 2011). TiO2 NPs are self-cleaning, non-toxic, chemically stable highly photo-reactive and have broad-spectrum antibiotic capability (Priyanka et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Titanium Oxide (TiO<sub>2</sub>) Nanoparticles for Treatment of Wound Infection

Alhadrami¹,

Shoudri²

2020

Preprint

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Wound infections evidently appeared in times of World War I that accounted a significant mortality and morbidity rate among injured soldiers. Currently, around 11 million people worldwide require medical treatment for wound infections and 300,000 die every year due to untreated wound infection. The extensive use of antibiotics to treat wound infection leads to emerging new microbial strains that are resistant to many antibiotics. There is a growing concern on the emergence and re-emergence of drug-resistant pathogens such as multi-resistant bacterial strains. Hence, the development of new antimicrobial compounds or the modification of those that already exist to improve antibacterial activity is a high priority area of research. During the past few decades, nanotechnology has arisen with new promising technology for synthesis of nanobiomaterials. Metallic nanoparticles (NPs) are considered as new alternative treatment with superior antibacterial activity. In this study, new formulation of titanium oxide (TiO2) NPs with different sizes were synthesized and characterized. Genotoxicity, mutagenicity and antibacterial activities of TiO2 NPs against the causative agents of wound infection were investigated. Antibacterial activity of TiO2 NPs was conducted against three ATCC ® bacterial strains: methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli and Pseudomonas aeruginosa. The results clearly illustrate a superior antibacterial activity of all newly formulated TiO2 NPs against the most causative agents of wound infection. Most of our TiO2 NPs showed non-genotoxic and non-mutagenic results at the maximum concentrations. Findings of this study will enhance the future of the therapeutic strategies against the resistant pathogenic strains that cause wound infections.

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“…Various metal nanoparticles (MNPs) have been used in diverse fields, ranging from environmental remediation and biomedicine to catalysis, opt-electronic materials, and sensors [1,2]. MNPs comprising silver [1,3,4], copper oxide [1,2,5], zinc oxide [1,2,6], titanium oxide [2,7], and calcium oxide (CaO) [8,9] have strong antimicrobial activity against most microorganisms, including bacteria, fungi, and viruses. CaO nanoparticles have been synthesized by solution combustion methods using Ca(NO) 3 and NH 2 CONH 2 dissolved in water [10,11].…”

Section: Introductionmentioning

confidence: 99%

Preparation and Application of Bioshell Calcium Oxide (BiSCaO) Nanoparticle-Dispersions with Bactericidal Activity

et al. 2019

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Scallop-shell powder (SSP) heated at high temperature exhibits high pH and broad antimicrobial activity. Bioshell calcium oxide (BiSCaO) is an SSP composed mainly of calcium oxide. It is poorly water-soluble under alkaline conditions and the generated precipitate can plug spray nozzles. The aim of this study was to establish that BiSCaO dispersion caused no significant CaO loss and plugging of spray nozzles, and to evaluate its deodorization and microbicidal abilities and its ability to reduce the concentrations of NO2− and NO3−. BiSCaO dispersions were prepared by mixing various concentrations of BiSCaO suspension, while phosphate compounds such as Na3PO4, Na2HPO4 or NaH2PO4 and the pH, average diameter, zeta potential, and form of the compounds with cryo-SEM were evaluated. We evaluated deodorization using tainted pork meat and microbicidal efficacy using contaminated suspension with normal bacterial flora. The concentration of NO2− and NO3− after mixing BiSCaO dispersion and pure water containing a high proportion of NO2− and NO3− were measured. BiSCaO dispersion formed with Na2HPO4, whose ratio to BiSCaO was 60%, showed a high pH (>12), a small particle diameter (>181 nm) and was stable for seven days. The BiSCaO dispersion showed higher deodorization and microbicidal activities than SSP-Ca(OH)2, which was mainly composed of Ca(OH)2. BiSCaO, but not SSP-Ca(OH)2, could reduce the concentration of NO2− and NO3− by more than 90% within 15 min. We developed a stable BiSCaO dispersion, and it had high deodorization and microbicidal efficacy. These activities of BiSCaO might result from the high pH caused by CaO hydration and a reduction activity causing active radical species.

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Microbicidal activity of TiO₂nanoparticles synthesised by sol–gel method

Cited by 49 publications

References 25 publications

Antibacterial activity of carbon nanoparticles isolated from chimney soot

Antibacterial activity of carbon nanoparticles isolated from chimney soot

Titanium Oxide (TiO<sub>2</sub>) Nanoparticles for Treatment of Wound Infection

Preparation and Application of Bioshell Calcium Oxide (BiSCaO) Nanoparticle-Dispersions with Bactericidal Activity

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Microbicidal activity of TiO2nanoparticles synthesised by sol–gel method

Cited by 49 publications

References 25 publications

Antibacterial activity of carbon nanoparticles isolated from chimney soot

Antibacterial activity of carbon nanoparticles isolated from chimney soot

Titanium Oxide (TiO<sub>2</sub>) Nanoparticles for Treatment of Wound Infection

Preparation and Application of Bioshell Calcium Oxide (BiSCaO) Nanoparticle-Dispersions with Bactericidal Activity

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Microbicidal activity of TiO₂nanoparticles synthesised by sol–gel method