Microbial keratitis as a foreseeable complication of cosmetic contact lenses: a prospective study

Sauer, Arnaud; Bourcier, Tristan

doi:10.1111/j.1755-3768.2011.02120.x

Cited by 59 publications

(46 citation statements)

References 19 publications

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“…De nombreux cas rapportés de kératites infectieuses sous lentilles de contact mettent en lumière divers facteurs de risque potentiels comme le port de lentilles cosmétiques (lentilles colorées à indication esthétique ou festive, planes ou correctrices), ou des erreurs grossières dans le maniement et l'entretien des lentilles [22][23][24][25]. Certaines solutions d'entretien sont efficaces sur les formes végétatives d'Acanthamoeba sp., mais ne le sont pas forcément sur les formes kystiques : les kystes, protégés par leur double paroi, présentent une résistance accrue.…”

Section: Discussionunclassified

Efficacité anti-amibienne in vitro de l’association riboflavine/UV-A

Letsch¹,

Abou-Bacar

Candolfi

et al. 2015

Journal Français d'Ophtalmologie

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Section: Discussionunclassified

Efficacité anti-amibienne in vitro de l’association riboflavine/UV-A

Letsch¹,

Abou-Bacar

Candolfi

et al. 2015

Journal Français d'Ophtalmologie

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“…[79][80][81][82] In a comparative risk study analysis of daily wear soft contact lens wear and LASIK, risk of long-term contact lens wear was higher than LASIK surgery for low to moderate myopia. 79,80 One of the main concerns with laser refractive surgery in younger children is requirement for general anaesthesia.…”

Section: Instrastromal Ring Implantation For Keratoconusmentioning

confidence: 99%

Update on Paediatric Refractive Surgery

Pirouzian¹,

Hashemian²,

Khodaparast³

2015

European Ophthalmic Review

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Purpose: To provide a summary of the most recent evidence-based data on the paediatric refractive surgery. Methods: A review of the published studies from 1990 to 2015 was undertaken with emphasis on recent articles from 2010 to 2015. Results: Searching Scopus and PubMed, using the keywords of refractive surgery, phakic, paediatric, IOL, children and amblyopia alone or in various combinations yielded a total of about 48 articles on this topic from 1990 to 2015. Excluding review articles, fewer than 35 articles were included. Original research articles were only in the form of case reports/series on corneal laser surgery and phakic intraocular lens implantation or clear lens extraction. A total of fewer than 800 patients and 700 eyes had undergone a form of refractive surgery listed above. No randomised clinical trial (RCT) study was available on the topic. Age varied from 7 months to 17 years for non-corneal cross-linking studies. Most commonly performed operations were corneal laser ablative procedures (photorefractive keratectomy [PRK], laser-assisted sub-epithelial keratectomy[LASEK], laser-assisted in situ keratomileusis [LASIK]), phakic intraocular lens implantations (p-IOL, anterior or posterior chamber) and clear lens extraction. The indications for surgical intervention were for refractive -high amplitude iso-ametropic or anisometropic -amblyopia in the setting of the previously failed medical interventions and spectacle intolerance or non-compliance (physical or neurobehavioral in nature) and high accommodative esotropia with/without amblyopia. The main objective of the studies was to assess for visual acuity gained or lost following surgery and for correction of strabismus, i.e. achieving orthophoria. Further search on the keywords 'cross-linking, cornea, rings and children' from the same databases resulted in 130 articles. No RCT study was available on the topic. Age varied from 7 months to 17 years for non-corneal cross-linking studies. The focus of the most recent refractive surgery articles has been on the treatment and stabilisation of irregular myopic astigmatism from kerato-ectatic conditions by means of corneal cross-linking and intrastromal ring/in-lay implantation. Discussion: Refractive surgery remains a controversial topic in paediatric age population. However, the evidence clearly supports refractive surgery for treatment of children with refractive amblyopia and for treatment of accommodative esotropia in children unable or unwilling to wear spectacles or contact lenses. Conclusion: Consensus exists among published authors that refractive surgery may be considered in children with refractive amblyopia after exhausting various therapeutic medical options for amblyopia. Published authors have universally endorsed undertaking prospective multi-centred RCTs to conclusively establish the long-term safety and efficacy of various types of refractive surgery in the paediatric patients of different age groups. KeywordsChildren, myopia, refractive surgery, laser, intraocular lens, anisometr...

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“…Die Verwendung von Kontaktlinsen wurde als der wichtigste ätiologische Risikofaktor der schweren infektiösen Keratitis erneut bestätigt [3,5,6]. Die Bedeutung und Dringlichkeit einer adäquaten Patientenaufklärung über Gefahren und Hygienemaßnahmen in Zusammenhang mit dem Gebrauch von Kontaktlinsen wird dadurch unterstrichen, daß in der Mehrzahl der hier untersuchten Fälle von KLAMK mindestens ein vermeidbarer Risikofaktor zu erheben war.…”

Section: Diskussionunclassified

Keimspektrum und Risikofaktoren der schweren mikrobiellen Keratitis

Steger

Speicher

Bechrakis

et al. 2012

Spektrum Augenheilkd.

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Background: Microbial keratitis is a potentially sight-threatening ophthalmologic emergency. A significantly increased incidence has been observed over the course of the past two decades, most likely due to facilitated commercial access to contact lenses. The aim of this study was to describe microbial characteristics, outcome, risk factors, and factors associated with adverse outcome in patients admitted to our hospital for treatment of severe microbial keratitis. Material and Methods: All cases admitted to were retrospectively analyzed, 43 cases were included into this study. Inclusion criteria were a symptom duration of less than four weeks at the time of admittance, diagnosis of microbial keratitis by culture or clinical improvement under antimicrobial therapy, and index cases. Negative outcome was defined as necessity of penetrating keratoplasty or enucleation and any final best-corrected visual acuity of ≤ 0.05 three months after admittance. Results: 79.1 % of all cases were of bacterial origin, 11.6 % caused by fungi, 9.3 % by acanthamoeba. Risk factors included contact lens wear in 55.8 %, chronic ocular surface disease in 27.9 % %, pretreatment with steroids in 16.3 %. Contact lens associated bacterial keratitis was caused by Pseudomonas aeruginosa in 66.7 %, Staphylococcus spp. was the predominant causative agent in cases without this risk factor (72.7 %). Pseudomonas keratitis was characterized by significantly shorter symptom duration before admittance. Adverse outcome was recorded in 32.6 % of all cases. Pretreatment with steroids and symptom duration before admittance of more than 3 days were associated with adverse outcome. Conclusions: Contact lens wear ist the most important risk factor for severe microbial keratitis. Pseudomonas aeruginosa is associated with contact lens related microbial keratitis and a fulminant clinical course. Topical pretreatment of microbial keratitis with steroids is associated with adverse outcome and protracted clinical course. Zusammenfassung: Hintergrund: Die mikrobiell bedingte Keratitis ist ein potentiell visusbedrohender Notfall, dessen Inzidenz in den vergangenen zwei Jahrzehnten durch die zunehmend verbreitete Anwendung von Kontaktlinsen sowie deren unbehinderte kommerzielle Verfügbarkeit zugenommen hat. Das Ziel dieser Studie war es, mikrobielle Charakteristika, Outcome, Risikofaktoren und negative prognostische Parameter der schweren und stationär behandlungsbedürftigen mikrobiellen Keratitiden zu identifizieren. Material und Methode: Nach retrospektiver Analyse aller an der Augenklinik Innsbruck stationär behandelten Fälle mikrobieller Keratitis von Jänner 2007 bis Juni 2010 wurden 43 Fälle inkludiert. Eingeschlossen wurden nur Indexfälle mit einer Symptomdauer vor Aufnahme von unter 4 Wochen und die Diagnose einer mikrobieller Keratitis aus einem positiven Keimnachweis und / oder klinischem Ansprechen auf entsprechende antimikrobielle Therapie. Als negatives Outcome wurden die Notwendigkeit einer perforierenden Keratoplastik, eine Enukleation und ein bestkorr...

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Microbial keratitis as a foreseeable complication of cosmetic contact lenses: a prospective study

Abstract: Patients who acquire CosCL are less likely to be instructed on appropriate lenses use and basic hygiene rules. Consequently, CosCL wearers are experiencing acute vision-threatening infections.

Cited by 59 publications

References 19 publications

Efficacité anti-amibienne in vitro de l’association riboflavine/UV-A

Efficacité anti-amibienne in vitro de l’association riboflavine/UV-A

Update on Paediatric Refractive Surgery

Keimspektrum und Risikofaktoren der schweren mikrobiellen Keratitis

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