Microbial ingress and in vitro degradation enhanced by glucose on bioabsorbable Mg–Li–Ca alloy

Evaluation of the Influence of Eggshell (ES) Concentration on the Degradation Behavior of Mg–2.5Zn Biodegradable Alloy in Simulated Body Fluid

“…On the other hand, the FTIR spectra of the decomposition products on the Mg samples showed the presence of phosphate PO 4 3– and carbonate signals (CO 3 2– ), which were detected after 28 days of immersion at 594 and 871 cm –1 , respectively , (see Figure b). The highest-intense peak at 1031 cm –1 is ascribed to the P–O asymmetric stretching vibration of PO 4 3– . , It is worth mentioning that P–O bands of apatite can be found at 604–560 and 1010–1090 cm –1 . , The stretching vibration of absorbed CO 3 2– species is responsible for the prominent peak at 1418 cm –1 . ,, The hydroxyl groups (OH – ) are responsible for the broad peak between 3000 and 3500 cm –1 . , Nevertheless, the weak peak of H 2 O bending vibrations was found at 1647 cm –1 . Therefore, PO 4 3– , CO 3 2– , and HPO 4 2– are detected in the infrared spectrum, suggesting that these functional groups contribute to corrosion products.…”

“…43,45,46 The hydroxyl groups (OH − ) are responsible for the broad peak between 3000 and 3500 cm −1 . 48,49 Nevertheless, the weak peak of H 2 O bending vibrations was found at 1647 cm −1 . Therefore, PO 4 3− , CO 3 2− , and HPO 4 2− are detected in the infrared spectrum, suggesting that these functional groups contribute to corrosion products.…”

Glucose microenvironment sensitive degradation of arginine modified calcium sulfate reinforced poly(lactide-co-glycolide) composite scaffolds

“…As a result, clinically, there is no significant difference in the treatment of diabetic osteoporosis and non-diabetic osteoporosis. Recently, the degradation of Mg 10 and its alloy 11 in response to glucose was reported, and the results suggested that the Mg–1Li–1Ca alloy exhibited different responses to Hank's solution with and without glucose. The encouraging results implied that the clinical biodegradable materials may possess distinct degradation behavior in high glucose environments from the usual one.…”

Preparation of HA-MAO coatings on β-type alloys and its corrosion resistance in high glucose environments

“…In diabetic patients, in addition to corrosion due to exposure to body uids, implants are exposed to the formation of a localized microenvironment, in particular the inhomogeneous accumulation of advanced glycation end products and inammatory factors (proteins) on the surface of the implant, which accelerates the electro-chemical corrosion reaction. 20,21 In the context of the corrosive effects of hyperglycemia on materials, studies conducted by R.-C. Zeng et al 22 have revealed that the presence of glucose expedites the corrosion rate of pure Mg materials in conventional physiological saline, whereas the corrosion rate is constrained when exposed to Hank's balanced salt solution. The researchers propose that glucose can undergo conversion to gluconic acid within physiological saline, thereby reducing the solution pH and promoting Cl − attack on the Mg surface, consequently accelerating the corrosion rate.…”