Microbial fermentation of blue honeysuckle (
Lonicera caeruleaL.) polyphenol promotes insulin secretion and intervenes in obesity by promoting short-chain fatty acids production
Fangyi Pei,
Xinbo Cao,
YanXin Ren
et al.
Abstract:During obesity treatment, clinicians have been burdened by the ever-increasing number of patients and the side effects of drug treatment. Finding new plant-derived active ingredients as an intervention for obesity has become a research focus. In this study, Plackett-Burman and Central Composite Design experiments, plant-wide target metabolomics technology, simulated human colon fermentation test, and cell experiment in vitro were successively used to investigate the effects of fermented and unfermented polyphe… Show more
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